Dextromethorphan Hydrobromide

• Catalog No.: Bio-0171
• CAS Number: 510-53-2
• M. F.: C18H26BrNO
• M. W.: 352.30914

SYNONYMS

• IUPAC name: (1R,9R,10R)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.0^1,^1^0.0^2,^7]heptadeca-2(7),3,5-triene hydrobromide
• IUPAC Traditional name: (1R,9R,10R)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.0^1,^1^0.0^2,^7]heptadeca-2(7),3,5-triene hydrobromide
• Synonyms: DXM; DM

DATABASE IDS

• CAS Number: 510-53-2

PROPERTIES

• Application(s): Antitussive
• Application(s): Anticonvulsant and neuroprotective props.
• Salt Data: HBr
• Mechanism of Action: NMDA receptor antagonist

REFERENCES

• Schnider, O. et al., Helv. Chim. Acta, 1950, 33, 1437; 1951, 34, 2211, (synth, resoln)
• Hfliger, D. et al., Helv. Chim. Acta, 1959, 39, 2053, (deriv)
• Corrodi, H. et al., Helv. Chim. Acta, 1959, 42, 212, (abs config)
• Yoshihiro, T. et al., Tet. Lett., 1975, 2853, (cmr)
• Gylbert, L. et al., Acta Cryst. B, 1977, 33, 2833, (deriv)
• Wainer, I.W. et al., J.O.C., 1982, 47, 1761, (deriv, resoln)
• Meyers, A.I. et al., J.O.C., 1986, 51, 872, (synth)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 4961, (synonyms)
• Tortella, F.C. et al., Trends Pharmacol. Sci., 1989, 10, 501, (pharmacol, rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 746
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DBE150; DBE200; DBE800; DYF000; LFG000; MKR250; MLZ000