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Mitiglinide

Catalog No. Bio-0162 Name InterBioScreen
CAS Number 145324-16-9 Website http://www.ibscreen.com
M. F. C19H25NO3 Telephone +7 49652 40091
M. W. 315.4067 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 179724

SYNONYMS

IUPAC name
4-[(3aR,7aS)-octahydro-1H-isoindol-2-yl]-2-benzyl-4-oxobutanoic acid
IUPAC Traditional name
4-[(3aR,7aS)-octahydro-1H-isoindol-2-yl]-2-benzyl-4-oxobutanoic acid
Synonyms
Glufast

DATABASE IDS

CAS Number 145324-16-9

PROPERTIES

Application(s) Oral hypoglycaemic agent for the treatment of type 2 diabetes
Mechanism of Action Stimulates insulin secretion

DETAILS

REFERENCES

  • Eur. Pat., 1992, Kissei, 507 534; CA, 118, 59584b, (synth, isomers, pharmacol)
  • Mogami, H. et al., Eur. J. Pharmacol., 1994, 269, 293-298, (pharmacol)
  • Malaisse, W.J., Horm. Metab. Res., 1995, 27, 263-266, (pharmacol)
  • Lins, L. et al., Biochem. Pharmacol., 1996, 52, 1155-1168, (pmr, cmr, pharmacol)
  • Kinukawa, M. et al., Br. J. Pharmacol., 1996, 117, 1702-1706, (pharmacol)
  • Ulusoy, S. et al., Diabetes Res., 1996, 31, 27-31, (pharmacol)
  • Sunaga, Y. et al., Eur. J. Pharmacol., 2001, 431, 119-125, (pharmacol)