Chlorpropamide

• Catalog No.: Bio-0154
• CAS Number: 94-20-2
• M. F.: C10H13ClN2O3S
• M. W.: 276.73982

SYNONYMS

• IUPAC name: 1-(4-chlorobenzenesulfonyl)-3-propylurea
• IUPAC Traditional name: 1-(4-chlorobenzenesulfonyl)-3-propylurea
• Synonyms: Melitase; Diabinese

DATABASE IDS

• CAS Number: 94-20-2

PROPERTIES

• Application(s): Oral antihyperglycaemic drug
• Application(s): Used to treat non-insulin dependent diabetes mellitus
• Mechanism of Action: Augmenting insulin secretion

REFERENCES

• Marshall, F.J. et al., J.O.C., 1958, 23, 927, (synth)
• Bauer, V.J. et al., J.O.C., 1960, 31, 3440, (synth)
• McManus, J.M. et al., J. Med. Chem., 1965, 8, 766, (pharmacol)
• Jackson, W.P.U., Med. Chem. (Academic Press), 1969, 9, 135, (pharmacol)
• Madsen, S.N. et al., Eur. J. Pharmacol., 1971, 13, 374, (metab)
• Dave, G.R. et al., Indian Chem. J., 1971, 5, 31, (synth)
• Kuhnert-Brandstaetter, M. et al., Sci. Pharm., 1974, 42, 150, (uv)
• Koo, C.H. et al., Arch. Pharmacal Res., 1980, 3, 37, (cryst struct)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1573, (synonyms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 277
• Mizuno, T. et al., Synth. Commun., 2000, 30, 3081-3089, (synth, ir, pmr, cmr)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CKK000