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Tamsulosin hydrochloride_Molecular_structure_CAS_106463-17-6)
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Tamsulosin hydrochloride

Catalog No. Bio-0146 Name InterBioScreen
CAS Number 106463-17-6 Website http://www.ibscreen.com
M. F. C20H29ClN2O5S Telephone +7 49652 40091
M. W. 444.97266 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 155796

SYNONYMS

IUPAC name
5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonamide hydrochloride
IUPAC Traditional name
5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonamide hydrochloride
Synonyms
Flomax

DATABASE IDS

CAS Number 106463-17-6

PROPERTIES

Application(s) Antineoplastic agent
Application(s) Used in the treatment of benign prostatic hyperplasia
Salt Data HCl
Mechanism of Action Prostate selective alpha 1-adrenoceptor antagonist

DETAILS

REFERENCES

  • Eur. Pat., 1981, Yamanouchi Pharm, 34432; CA, 96, 19812v, (synth)
  • Honda, K. et al., J. Pharmacol. Exp. Ther., 1986, 239, 512; 1990, 253, 427, (pharmacol)
  • Honda, K. et al., J. Pharm. Pharmacol., 1987, 39, 316
  • Honda, K. et al., Naunyn-Schmiedeberg's Arch. Pharmacol., 1987, 336, 295, (pharmacol)
  • Lepor, H. et al., Br. J. Pharmacol., 1988, 95, 139; 702, (activity)
  • Wheeler, W.J. et al., J. Labelled Compd. Radiopharm., 1989, 27, 171, (synth)
  • Yazawa, H. et al., J. Pharmacol. Exp. Ther., 1992, 263, 201, (pharmacol)
  • Ratnasooriya, W.D. et al., Andrologia, 1994, 26, 107, (tox)
  • Jonler, M. et al., Drugs, 1994, 47, 66, (use)
  • Rabasseda, X. et al., Drugs of Today (Barcelona), 1996, 32, 259, (rev)
  • Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 951