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Doxifluridine Hydrochloride_Molecular_structure_CAS_3094-09-5)
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Doxifluridine Hydrochloride

Catalog No. Bio-0124 Name InterBioScreen
CAS Number 3094-09-5 Website http://www.ibscreen.com
M. F. C9H12ClFN2O5 Telephone +7 49652 40091
M. W. 282.6533832 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 120168

SYNONYMS

IUPAC name
1-[(3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione hydrochloride
IUPAC Traditional name
1-[(3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione hydrochloride

DATABASE IDS

CAS Number 3094-09-5

PROPERTIES

Application(s) Antineoplastic agent
Salt Data HCl
Mechanism of Action Prodrug of 5-Fluoro-2,4(1 H ,3 H) -pyrimidinedione

DETAILS

REFERENCES

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  • Scott, J.W. et al., J. Carbohydr., Nucleosides, Nucleotides, 1981, 8, 171, (synth)
  • Kiss, J. et al., Helv. Chim. Acta, 1982, 65, 1522, (synth)
  • Sommadossi, J.P. et al., Cancer Res., 1983, 43, 930, (metab)
  • Kono, A. et al., Chem. Pharm. Bull., 1983, 31, 1666, (hplc)
  • Sommadossi, J.P. et al., Int. Congr. Ser. Excerpta Med., 1984, 647, 108, (pharmacol, metab)
  • Meynial, D. et al., J. Pharm. Pharmacol., 1986, 38, 426, (metab)
  • Au, J.L.S. et al., J. Pharm. Sci., 1987, 76, 699, (metab)
  • Guerrieri, A. et al., J. Chromatogr., 1993, 617, 71, (hplc)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 475
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DYE415