Ciprofibrate

• Catalog No.: Bio-0119
• CAS Number: 52214-84-3
• M. F.: C13H14Cl2O3
• M. W.: 289.15446

SYNONYMS

• IUPAC name: 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
• IUPAC Traditional name: 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
• Synonyms: Ciprol; Lipanor

DATABASE IDS

• CAS Number: 52214-84-3

PROPERTIES

• Application(s): Hypolipidaemic agent
• Application(s): Effective in type Iia, Iib, III and IV hyperlipoproteinaemias and increases high-density lipoprotein
• Mechanism of Action: Agonist of the PPARalpha receptor in muscle, liver, and other tissues

REFERENCES

• Fr. Pat., 1974, Sterling Drug, 2 197 586; CA, 82, 43059m, (synth, pharmacol)
• Arnold, A. et al., J. Pharm. Sci., 1979, 68, 1557, (props)
• Beyer, K.H. et al., Arch. Pharm. (Weinheim, Ger.), 1982, 315, 1049, (metab)
• Gibson, G. et al., Peroxisomes: Biology and Importance in Toxicology and Medicine, Taylor and Francis, London, 1993, (rev)
• Chapman, M.J. et al., Atherosclerosis (Amsterdam), 1996, 124; S83, (pharmacol, use)
• Masnatta, L.D. et al., J. Chromatogr., B: Biomed. Appl., 1996, 687, 437, (hplc)
• Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 1304
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CMS210