Betaxolol Hydrochloride

• Catalog No.: Bio-0117
• CAS Number: 116209-55-3
• M. F.: C18H30ClNO3
• M. W.: 343.8887

SYNONYMS

• IUPAC name: [(2S)-3-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-2-hydroxypropyl](propan-2-yl)amine hydrochloride
• IUPAC Traditional name: [(2S)-3-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-2-hydroxypropyl](propan-2-yl)amine hydrochloride
• Synonyms: Levobetaxolol hydrochloride

DATABASE IDS

• CAS Number: 116209-55-3

PROPERTIES

• Application(s): Antianginal
• Application(s): Antihypertensive agent
• Application(s): Used to control intraocular pressure
• Salt Data: HCl
• Mechanism of Action: beta 1 -Adrenoceptor antagonist

REFERENCES

• Ger. Pat., 1977, Synthelabo, 2 649 605; CA, 87, 134543j, (synth, tox)
• Cadigan, P.J. et al., Br. J. Clin. Pharmacol., 1980, 9, 569, (pharmacol)
• Morselli, P.N. et al., L.E.R.S. Monogr. Ser., Vol. 1, 1983, (book)
• Pascard, C. et al., Acta Cryst. C, 1984, 40, 1430, (cryst struct)
• Vermeij, P., Pharm. Weekbl., 1984, 119, 1198, (rev)
• Beresford, R. et al., Drugs, 1986, 31, 6, (rev)
• Manoury, P.M. et al., J. Med. Chem., 1987, 30, 1003, (synth, pharmacol, isomers)
• Buckley, M.M.-T. et al., Drugs, 1990, 40, 75, (rev)
• Olsen, L. et al., J. Chromatogr., 1993, 636, 231, (hplc)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 630
• Jira, T. et al., Pharmazie, 1993, 48, 829, (hplc, resoln)
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• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 6750, (synonyms)
• Di Bono, G. et al., Synthesis, 1995, 699, (S-form)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, KEA350