Amisulpride

• Catalog No.: Bio-0114
• CAS Number: 71675-85-9
• M. F.: C17H27N3O4S
• M. W.: 369.47898

SYNONYMS

• IUPAC name: 4-amino-5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide
• IUPAC Traditional name: 4-amino-5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide
• Synonyms: Socian; Enorden; Solian; Majorem; Deniban; Aminosultopride

DATABASE IDS

• CAS Number: 71675-85-9

PROPERTIES

• Application(s): Antiemetic and spasmolytic agent
• Application(s): Psychotherapeutic (autism)
• Application(s): Antipsychotic
• Application(s): Neuroleptic agent
• Mechanism of Action: Spasmolytic
• Mechanism of Action: Dopamine D 2 /D 3 -receptor antagonist

REFERENCES

• U.S. Pat., 1979, 4 294 828; CA, 91, 211113f, (synth, pharmacol)
• Hanocq, M. et al., Pharm. Acta Helv., 1982, 57, 37, (uv, ir)
• Bohbot, M. et al., J. Chromatogr., 1987, 416, 414, (hplc)
• De Winter, H.L. et al., Acta Cryst. C, 1990, 46, 313, (cryst struct)
• Mannhold, R. et al., Quant. Struct.-Act. Relat., 1990, 9, 21, (log P)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 565
• Noble, S. et al., CNS Drugs, 1999, 12, 471-483, (rev)
• Curran, M.P. et al., Drugs, 2001, 61, 2123-2150, (rev)