Zolmitriptan

• Catalog No.: Bio-0113
• CAS Number: 139264-82-7
• M. F.: C16H21N3O2
• M. W.: 287.35684

SYNONYMS

• IUPAC name: 4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
• IUPAC Traditional name: 4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
• Synonyms: Zomig

DATABASE IDS

• CAS Number: 139264-82-7

PROPERTIES

• Application(s): Antimigraine agent
• Mechanism of Action: 5-Hydroxytryptamine (5HT1D) receptor agonist
• Mechanism of Action: Selective Serotonin receptor agonist

REFERENCES

• Pat. Coop. Treaty (WIPO), 1991, Wellcome, 91 18 897; CA, 116, 174136c, (synth, pharmacol)
• Goadsby, P.J. et al., Headache, 1994, 34, 394, (pharmacol)
• Glen, R.C. et al., J. Med. Chem., 1995, 38, 3566, (synth, pharmacol, sar)
• Buckingham, J. et al., J. Med. Chem., 1995, 38, 3566-3580, (synth, pharmacol)
• Dowson, A., Eur. Neurol., 1996, 36, 28-31, (pharmacol)
• MacGregor, E.A. et al., Drugs of the Future, 1998, 34, 1027-1033
• Spencer, C.M. et al., Drugs, 1999, 58, 347-374