Vinblastine

• Catalog No.: Bio-0111
• CAS Number: 865-21-4
• M. F.: C46H58N4O9
• M. W.: 810.97412

SYNONYMS

• IUPAC name: methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• IUPAC Traditional name: methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• Synonyms: Vincaleukoblastine; Vincaleucoblastine

DATABASE IDS

• CAS Number: 865-21-4

PROPERTIES

• Application(s): Antineoplastic agent
• Application(s): Used widely in the treatment of Hodgkin's disease and other lymphomas
• Biological Source: Alkaloid from Vinca rosea ( Catharanthus roseus ) (Apocynaceae)
• Mechanism of Action: Binds tubulin, inhibiting the assembly of microtubules

REFERENCES

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