Telmisartan

• Catalog No.: Bio-0103
• CAS Number: 144701-48-4
• M. F.: C33H30N4O2
• M. W.: 514.6169

SYNONYMS

• IUPAC name: 2-(4-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid
• IUPAC Traditional name: 2-(4-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid
• Synonyms: Teleact D; Telma; Kinzal; Micardis; Pritor

DATABASE IDS

• CAS Number: 144701-48-4

PROPERTIES

• Application(s): Antihypertensive agent
• Mechanism of Action: Angiotensin II (AT 1 ) receptor antagonist

REFERENCES

• Eur. Pat., 1992, Thomae, 502 314; CA, 117, 251352v, (synth, pharmacol)
• Wienen, W. et al., Br. J. Pharmacol., 1993, 110, 245, (pharmacol)
• Ries, U.J. et al., J. Med. Chem., 1993, 36, 4040, (synth, pmr, pharmacol)
• Su, C.A.P.F. et al., Clin. Pharmacol. Ther. (St. Louis), 1994, 55, 205, (pharmacol)
• Bhm, M. et al., J. Hypertens., 1995, 13, 891, (pharmacol)
• van Meel, J.C.A. et al., Arzneim.-Forsch., 1996, 46, 755, (pharmacol)
• McClellan, K.J. et al., Drugs, 1998, 56, 1039-1044, (rev)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 951
• Gavras, I. et al., Cardiovasc. Rev. Rep., 2000, 21, 76
• Sharpe, M. et al., Drugs, 2001, 61, 1501-1529, (rev)