Salbutamol Sulphate

• Catalog No.: Bio-0095
• CAS Number: 51022-70-9
• M. F.: C13H23NO7S
• M. W.: 337.38922

SYNONYMS

• IUPAC name: 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol; sulfuric acid
• IUPAC Traditional name: 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol; sulfuric acid
• Synonyms: Albuterol Sulfate

DATABASE IDS

• CAS Number: 51022-70-9

PROPERTIES

• Application(s): Bronchodilator
• Application(s): Antiasthmatic agent
• Application(s): Muscle relaxant
• Application(s): Topical antiinflammatory agent
• Salt Data: H2SO4
• Mechanism of Action: Bronchodilator
• Mechanism of Action: Beta-Adrenoceptor agonist

REFERENCES

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• Hartley, D. et al., J. Med. Chem., 1971, 14, 895, (abs config)
• Beale, J.P. et al., Cryst. Struct. Commun., 1972, 1, 71, (cryst struct)
• Hawkins, C.J. et al., J. Med. Chem., 1973, 16, 856, (synth, isom)
• Brittain, R.T. et al., Pharmacol. Biochem. Prop. Drug Subst., 1977, 1, 257, (rev, pharmacol)
• Pasaribu, S.J. et al., Aust. J. Chem., 1978, 31, 2629, (cmr)
• Aboul-Enein, H.Y. et al., Anal. Profiles Drug Subst., 1981, 10, 665, (rev, synth, anal)
• Ahrens, R.C. et al., Pharmacotherapy (Carlisle, Mass.), 1984, 4, 105, (rev, pharmacol)
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• Libretto, S.E. et al., Arch. Toxicol., 1994, 68, 213, (tox, rev)
• Johnson, M. et al., Asthma and Rhinitis, (Eds. Busse, W.W. et al), Blackwell Science, 1995, 1278, (rev)
• Effenberger, F. et al., J.O.C., 1997, 62, 3867, (synth)
• Regla, I. et al., Synth. Commun., 1997, 27, 817-823, (synth, pmr, cmr)
• Handley, D.A. et al., Expert Opin. Invest. Drugs, 1998, 7, 2027
• J. Allergy Clin. Immunol., 1999, 104, S31-S41; S61-S68; S69-S76; S77-S84
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 758
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, BQF500; SAF400