Prazosin hydrochloride

• Catalog No.: Bio-0082
• CAS Number: 19237-84-4
• M. F.: C19H22ClN5O4
• M. W.: 419.86208

SYNONYMS

• IUPAC name: 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine hydrochloride
• IUPAC Traditional name: 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine hydrochloride
• Synonyms: Furazosin

DATABASE IDS

• CAS Number: 19237-84-4

PROPERTIES

• Application(s): Antihypertensive agent
• Salt Data: HCl
• Mechanism of Action: Alpha 2B -Adrenoceptor antagonist,
• Mechanism of Action: Melatonin MT 3 -receptor antagonist

REFERENCES

• Brogden, R.N. et al., Drugs, 1977, 14, 163, (rev, pharmacol)
• Honkanen, E. et al., Finn. Chem. Lett., 1979, 20, (ms)
• Honkanen, E. et al., J. Het. Chem., 1980, 17, 797, (synth, bibl)
• Cavero, I. et al., Life Sci., 1980, 27, 1525, (rev, pharmacol)
• Rawlins, M.D., Prazosin: Pharmacol., Hypertens. Congestive Heart Failure, (Ed.), Grune and Stratton, N.Y., 1981, (book)
• Reid, J.L. et al., Cardiology, 1986, 73, 164, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 5260
• Kostek, L.J., Anal. Profiles Drug Subst., 1989, 18, 351, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 384
• Luchelli, A. et al., Br. J. Pharmacol., 1997, 121, 1775-1781, (pharmacol)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AJP000; FPP100