Olmesartan

• Catalog No.: Bio-0071
• CAS Number: 144689-24-7
• M. F.: C29H30N6O6
• M. W.: 558.5851

SYNONYMS

• IUPAC name: (5-methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylate
• IUPAC Traditional name: (5-methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylate
• Synonyms: Benicar; Olmetec

DATABASE IDS

• CAS Number: 144689-24-7

PROPERTIES

• Application(s): Antihypertensive agent
• Mechanism of Action: Prodrug-type angiotensin II receptor antagonist
• Mechanism of Action: Angiotensin II receptor antagonists
• Mechanism of Action: Block the binding of angiotension II to the AT1 receptors in vascular muscle

REFERENCES

• Eur. Pat., 1992, Sankyo, 503 785; CA, 118, 22240k, (CS 866, RNH 6270, synth, pharmacol)
• Mizuno, M. et al., Eur. J. Pharmacol., 1995, 285, 181-188, (pharmacol, CS 866, RNH 6270)
• Yanagisawa, H. et al., J. Med. Chem., 1996, 39, 323-328, (synth, CS 866, RNH 6270, pmr, ir, pharmacol)