Home > Compound List > Product Information
Nateglinide_Molecular_structure_CAS_105816-04-4)
Click picture or here to close

Nateglinide

Catalog No. Bio-0067 Name InterBioScreen
CAS Number 105816-04-4 Website http://www.ibscreen.com
M. F. C19H27NO3 Telephone +7 49652 40091
M. W. 317.42258 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 73040

SYNONYMS

IUPAC name
(2R)-3-phenyl-2-{[(1r,4r)-4-(propan-2-yl)cyclohexyl]formamido}propanoic acid
IUPAC Traditional name
(2R)-3-phenyl-2-{[(1r,4r)-4-(propan-2-yl)cyclohexyl]formamido}propanoic acid
Synonyms
Starsis
Fastic
Starlix

DATABASE IDS

CAS Number 105816-04-4

PROPERTIES

Application(s) Oral hypoglycaemic agent
Application(s) Antidiabetic agent
Mechanism of Action Stimulats the release of insulin from the pancreas by closing ATP-dependent potassium channels in the membrane of the betta-cells

DETAILS

REFERENCES

  • Fujita, T. et al., Biochem. Pharmacol., 1996, 52, 407-411, (pharmacol)
  • Takesda, H. et al., Bioorg. Med. Chem. Lett., 1996, 4, 1771-1781, (metab)
  • Ono, I. et al., J. Chromatogr., B: Biomed. Appl., 1996, 678, 384-387; 1997, 692, 397-404, (hplc)
  • Ikenoue, T. et al., Br. J. Pharmacol., 1997, 120, 137-145; 1191-1198, (pharmacol)
  • Dunn, C.J. et al., Drugs, 2000, 60, 607-615, (rev)
  • Eur. Pat., 1986, Ajinomoto, 196 222; CA, 106, 85057d, (synth, pharmacol)
  • Hirose, H. et al., Pharmacology, 1994, 48, 205-210; 1995, 50, 175-181; 51, 245-253, (pharmacol)
  • Akiyoshi, M. et al., Am. J. Physiol., 1995, 268, E185-E193, (pharmacol)
  • Malaisse, W.J. et al., Horm. Metab. Res., 1995, 27, 263-266, (pharmacol)