Montelukast Sodium

• Catalog No.: Bio-0064
• CAS Number: 151767-02-1
• M. F.: C35H35ClNNaO3S
• M. W.: 608.16507

SYNONYMS

• IUPAC name: sodium 2-(1-{[(1-{2-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[3-(2-hydroxypropan-2-yl)phenyl]propyl)sulfanyl]methyl}cyclopropyl)acetate
• IUPAC Traditional name: sodium 2-(1-{[(1-{2-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[3-(2-hydroxypropan-2-yl)phenyl]propyl)sulfanyl]methyl}cyclopropyl)acetate

DATABASE IDS

• CAS Number: 151767-02-1

PROPERTIES

• Application(s): Antiasthmatic agent
• Salt Data: Na+
• Mechanism of Action: Leukotriene LTD4 receptor antagonist

REFERENCES

• Eur. Pat., 1992, Merck Frosst Canada, 480 717; CA, 117, 90163, (synth)
• Labelle, M. et al., Bioorg. Med. Chem. Lett., 1995, 5, 283, (synth, pharmacol, sar)
• Jones, T.R. et al., Can. J. Physiol. Pharmacol., 1995, 73, 191, (pharmacol)
• Amin, R.D. et al., J. Pharm. Biomed. Anal., 1995, 13, 155, (hplc)
• Reiss, T.F. et al., J. Allergy Clin. Immunol., 1996, 98, 528, (use)
• Cheng, H. et al., Pharm. Res., 1996, 13, 445, (pharmacokinet, man)
• Markham, A. et al., Drugs, 1998, 56, 251-256, (rev)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 756
• Jarvis, B. et al., Drugs, 2000, 59, 891-928