Mometasone Furoate

• Catalog No.: Bio-0063
• CAS Number: 83919-23-7
• M. F.: C27H30Cl2O6
• M. W.: 521.4295

SYNONYMS

• IUPAC name: (1R,2S,13R,14R,15S,17S)-1-chloro-14-(2-chloroacetyl)-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl furan-2-carboxylate
• IUPAC Traditional name: (1R,2S,13R,14R,15S,17S)-1-chloro-14-(2-chloroacetyl)-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl furan-2-carboxylate
• Synonyms: Elocon; Elocom

DATABASE IDS

• CAS Number: 83919-23-7

PROPERTIES

• Application(s): Antiinflammatory
• Application(s): Antiallergic agent
• Mechanism of Action: Glucocorticoid steroid

REFERENCES

• Shapiro, E.L. et al., J. Med. Chem., 1987, 30, 1581, (synth, pharmacol, deriv)
• Popper, T.L. et al., J. Steroid Biochem., 1987, 27, 837, (pharmacol)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 737
• Prakash, A. et al., Drugs, 1998, 55, 145-163, (pharmacol, rev)
• Onrust, S.V. et al., Drugs, 1998, 56, 725-745, (mometasone furoate, rev)
• Draper, R.W. et al., Tetrahedron, 1999, 55, 3355-3364, (furoate, synth)
• Sharpe, M. et al., Drugs, 2001, 61, 1325-1350, (rev)