Loratadine

• Catalog No.: Bio-0059
• CAS Number: 79794-75-5
• M. F.: C22H23ClN2O2
• M. W.: 382.88322

SYNONYMS

• IUPAC name: ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene}piperidine-1-carboxylate
• IUPAC Traditional name: ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene}piperidine-1-carboxylate
• Synonyms: Clarityn; Claritine; Claritin; Fristamin; Loratadine; Claritin-D; Clarityne

DATABASE IDS

• CAS Number: 79794-75-5

PROPERTIES

• Application(s): Used in the treatment of rhinitis and skin disorders
• Application(s): Other pharmacol. mechanisms under investigation
• Mechanism of Action: Histamine H1-receptor antagonist

REFERENCES

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• Clissold, S.P. et al., Drugs, 1989, 37, 42, (rev)
• Schumacher, D.P. et al., J.O.C., 1989, 54, 2242, (synth, pmr)
• Piwinski, J.J. et al., J.O.C., 1990, 55, 3341, (metab)
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