Ipratropium Bromide

• Catalog No.: Bio-0052
• CAS Number: 22254-24-6
• M. F.: C20H30BrNO3
• M. W.: 412.3611

SYNONYMS

• IUPAC name: (1R,3R,5S)-3-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-8-methyl-8-(propan-2-yl)-8-azabicyclo[3.2.1]octan-8-ium bromide
• IUPAC Traditional name: (1R,3R,5S)-3-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-8-methyl-8-(propan-2-yl)-8-azabicyclo[3.2.1]octan-8-ium bromide
• Synonyms: Berodual; Rinatec; Atrovent; Respontin; Atem; Itrop; Narilet; Normosecretol; Tropiovent

DATABASE IDS

• CAS Number: 22254-24-6

PROPERTIES

• Application(s): Bronchodilator
• Application(s): Antimuscarinic agent
• Application(s): Antiarrhythmic
• Application(s): Antispasmodic agent
• Salt Data: Br-
• Mechanism of Action: Bronchodilator
• Mechanism of Action: Blocker of muscarinic receptors in the lung, inhibiting bronchoconstriction and mucus secretion

REFERENCES

• South African Pat., 1968, Boehringer Ingelheim, 6 707 766; CA, 70, 97033u, (synth, pharmacol)
• Pook, K.H. et al., Annalen, 1975, 1499, (nmr)
• Deckers, W., Postgrad. Med. J., Suppl., No. 7, 1975, 51, 76, (synth, pharmacol)
• Bauer, R. et al., Arzneim.-Forsch., 1976, 26, 974, (pharmacol)
• Sarajana, L. et al., Arzneim.-Forsch., 1976, 26, 985, (tox)
• Bauer, R. et al., Pharmacol. Biochem. Prop. Drug Subst., 1979, 2, 489, (rev)
• Massey, K.L. et al., Drug Intell. Clin. Pharm., 1985, 19, 5, (rev)
• Gross, N.J. et al., N. Engl. J. Med., 1988, 319, 486, (rev, pharmacol)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 8062, (synonyms)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 754
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, IGG000