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Frusemide

Catalog No. Bio-0044 Name InterBioScreen
CAS Number 54-31-9 Website http://www.ibscreen.com
M. F. C12H11ClN2O5S Telephone +7 49652 40091
M. W. 330.74414 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 577

SYNONYMS

IUPAC name
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
IUPAC Traditional name
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
Synonyms
Lasix
Tenkafruse
Froop
Fursemide
Diurapid
Frumax
Frusid
Frusol
Dryptal
Rusyde

DATABASE IDS

CAS Number 54-31-9

PROPERTIES

Application(s) Antihypertensive
Application(s) Diuretic
Application(s) Used for treatment of cirrhotic patients with ascites.
Application(s) Used in conjunction with Spironolactone HJR81-N for prophylaxis of hypokalaemia and hepatic encephalopathy or in treatment of hyperaldosteronism
Mechanism of Action Inhibitor of carbonic anhydrase,
Mechanism of Action subtype-specific blocker of GABA-A receptors

DETAILS

REFERENCES

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  • Du Souich, P. et al., Prog. Pharmacol. Clin. Pharmacol., 1992, 9, 147, (rev)
  • Aspects of Diuretic Therapy with Furosemide: an Update, Wells Medical, 1993, (book)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 2766, (synonyms)
  • Stanker, L.H. et al., J. Agric. Food Chem., 1996, 44, 2455-2459, (occur)
  • Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 871
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CHJ750
  • Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 591A, (ir)
  • Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 41C, (nmr)
  • Sturm, K. et al., Chem. Ber., 1966, 99, 328; 345, (synth, props)
  • Prandota, J. et al., Eur. J. Drug Metab. Pharmacokinet., 1976, 1, 177, (rev, metab)
  • Lamotte, J. et al., Acta Cryst. B, 1978, 34, 1657, (cryst struct)
  • Benet, L.Z., J. Pharmacokinet. Biopharm., 1979, 7, 1, (rev)
  • Rupp, W. et al., Arch. Int. Pharmacodyn. Ther., Suppl., 1980, 119, (rev, pharmacol)