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Etoposide

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CAS Number 33419-42-0 Website http://www.ibscreen.com
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SYNONYMS

IUPAC name
(10R,11R,15R,16S)-16-{[(2R,4aR,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.03,7.011,15]hexadeca-1,3(7),8-trien-12-one
IUPAC Traditional name
(10R,11R,15R,16S)-16-{[(2R,4aR,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.03,7.011,15]hexadeca-1,3(7),8-trien-12-one
Synonyms
Etopophos
Citodox
Vepesid
Vepeside
Exitop
Vespid
Abiposid
Amizide
Toposar

DATABASE IDS

CAS Number 33419-42-0

PROPERTIES

Application(s) Antineoplastic agent
Mechanism of Action DNA topoisomerase II inhibitor

DETAILS

REFERENCES

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  • Arnold, A.M. et al., Lancet, 1981, 2, 912, (rev)
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  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 10960, (synonyms)
  • Hainsworth, J.D. et al., Ann. Oncol., 1995, 6, 325, (pharmacol, rev)
  • Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 532
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, EAV500