Domperidone Maleate

• Catalog No.: Bio-0028
• CAS Number: 57808-66-9
• M. F.: C26H28ClN5O6
• M. W.: 541.98342

SYNONYMS

• IUPAC name: (2Z)-but-2-enedioic acid; 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
• IUPAC Traditional name: (2Z)-but-2-enedioic acid; 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one

DATABASE IDS

• CAS Number: 57808-66-9

PROPERTIES

• Application(s): Antiemetic drug
• Salt Data: Maleate
• Mechanism of Action: Antidopaminergic
• Mechanism of Action: Dopamine D2 antagonist

REFERENCES

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• Brogden, R.N. et al., Drugs, 1982, 24, 360, (rev, pharmacol)
• Emanuel, M.B. et al., Clin. Res. Rev., 1983, 3, 15; 57; 91, (revs)
• Kennis, L.E.J. et al., Drug Dev. Res., 1986, 8, 133, (synth, props)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 882
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 8895
• Prakash, A. et al., Drugs, 1998, 56, 429-445, (rev)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DYB875