Difloxacin hydrochloride

• Catalog No.: Bio-0027
• CAS Number: 98106-17-3
• M. F.: C21H20ClF2N3O3
• M. W.: 435.8516064

SYNONYMS

• IUPAC name: 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
• IUPAC Traditional name: 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

DATABASE IDS

• CAS Number: 98106-17-3

PROPERTIES

• Application(s): Antibacterial agent
• Salt Data: HCl
• Mechanism of Action: DNA gyrase inhibitor

REFERENCES

• Chu, D.T.W. et al., J. Med. Chem., 1985, 28, 1558, (synth, pharmacol)
• Fernandes, P.B. et al., Antimicrob. Agents Chemother., 1986, 29, 201, (pharmacol)
• Granneman, G.R. et al., Antimicrob. Agents Chemother., 1986, 30, 689, (metab)
• Granneman, G.R. et al., J. Chromatogr., 1987, 413, 199, (hplc)
• Shen, L.L. et al., Biochemistry, 1989, 28, 3886, (mech, sar)
• Xiao, W. et al., J. Pharm. Sci., 1989, 78, 585, (activity)
• Burkhardt, J.E. et al., Vet. Pathol., 1990, 27, 162, (tox)
• Burkhardt, J.E. et al., Fundam. Appl. Toxicol., 1993, 20, 257, (tox)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 159