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Cisapride

Catalog No. Bio-0018 Name InterBioScreen
CAS Number 81098-60-4 Website http://www.ibscreen.com
M. F. C23H31ClFN3O5 Telephone +7 49652 40091
M. W. 483.9607432 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 179692

SYNONYMS

IUPAC name
4-amino-5-chloro-N-[(4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide hydrate
IUPAC Traditional name
4-amino-5-chloro-N-[(4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide hydrate
Synonyms
Propulsin
Alimix
Kinet
Prepulsid
Arcasin
Cipril
Cyprid
Fisiogastrol
Kelosal
Propulsid
Pulsitil
Trautil

DATABASE IDS

CAS Number 81098-60-4

PROPERTIES

Application(s) Stimulates gut smooth muscle
Application(s) Increases gastrointestinal motility (prokinetic agent)
Application(s) Used in the management of GI reflux, dyspepsia
Salt Data H2O
Mechanism of Action 5HT(4) agonist

DETAILS

REFERENCES

  • Cooke, H.J. et al., Eur. J. Pharmacol., 1984, 98, 147, (pharmacol)
  • Eur. Pat., 1985, Janssen, 76 530; CA, 99, 194812d, (synth)
  • Van Daele, G.H.P. et al., Drug Dev. Res., 1986, 8, 225, (synth, pharmacol)
  • Reyntjens, A. et al., Drug Dev. Res., 1986, 8, 251, (rev)
  • McCallum, R.W. et al., Drugs, 1988, 36, 652, (rev)
  • Woestenborghs, R. et al., J. Chromatogr., 1988, 424, 195, (hplc)
  • Hopkins, S.J., Drugs of Today (Barcelona), 1989, 25, 637, (rev)
  • Collin, S. et al., J. Mol. Struct., 1989, 214, 159-175, (cryst struct)
  • Awouters, F.H.L. et al., Arzneim.-Forsch., 1991, 41, 631, (pharmacol)
  • Barone, J.A. et al., Ann. Pharmacother., 1994, 28, 488, (pharmacol)
  • Wiseman, L.R. et al., Drugs, 1994, 47, 116, (rev)
  • Peeters, O.M. et al., Acta Cryst. C, 1997, 53, 597-599, (cryst struct, tartrate)
  • Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 1187
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CMS237