Carvedilol

• Catalog No.: Bio-0014
• CAS Number: 72956-09-3
• M. F.: C24H26N2O4
• M. W.: 406.47424

SYNONYMS

• IUPAC name: [3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-methoxyphenoxy)ethyl]amine
• IUPAC Traditional name: [3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-methoxyphenoxy)ethyl]amine
• Synonyms: Coreg; Dilatrend

DATABASE IDS

• CAS Number: 72956-09-3

PROPERTIES

• Application(s): Vasodilator
• Mechanism of Action: Beta-Adrenoceptor blocker
• Mechanism of Action: Calcium channel blocker

REFERENCES

• Ger. Pat., 1984, 2 815 926; CA, 92, 128716e, (synth)
• Ger. Pat., 1984, 3 319 027; CA, 102, 113292, (resoln)
• Cubeddu, L.X. et al., Clin. Pharmacol. Ther. (St. Louis), 1987, 41, 31, (pharmacol)
• Abshagen, U., J. Cardiovasc. Pharmacol., (Suppl. 11), 1987, 10, S23, (rev, pharmacol)
• Sponer, G. et al., J. Cardiovasc. Pharmacol., (Suppl. 11), 1987, 10, S49, (pharmacol)
• Reiff, K., J. Chromatogr., 1987, 413, 355, (hplc)
• Neugebauer, G. et al., Eur. J. Clin. Pharmacol., 1990, 38, S108, (pharmacol, isomers)
• Ruffolo, R.R. et al., Cardiovasc. Drug Rev., 1992, 10, 127, (rev)
• McTavish, D. et al., Drugs, 1993, 45, 232, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 632
• Beta-blockers in Clinical Practice, (Eds. Cruickshank, J.M. et al), 2nd edn., Churchill Livingstone, 1994, 1119, (book)
• Dunn, C.J., Drugs, 1997, 53, 161-185, (rev)
• Rabasseda, X. et al., Drugs of Today (Barcelona), 1998, 34, 905-926
• Wood, A.J.J. et al., N. Engl. J. Med., 1998, 339, 1759-1765, (rev)