Carbidopa

• Catalog No.: Bio-0013
• CAS Number: 28860-95-9
• M. F.: C10H14N2O4
• M. W.: 226.22916

SYNONYMS

• IUPAC name: (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
• IUPAC Traditional name: (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
• Synonyms: Lodosyn; Lodysin; Menesit; Neo-Dopaston

DATABASE IDS

• CAS Number: 28860-95-9

PROPERTIES

• Application(s): Antiparkinsonian agent
• Application(s): Used in treatment of parkinsonism
• Mechanism of Action: Dopa-decarboxylase inhibitor

REFERENCES

• Karady, S. et al., J.O.C., 1971, 36, 1949, (synth)
• Lotti, V., Adv. Neurol., 1973, 2, 91, (rev, pharmacol)
• Rao, S.K. et al., Adv. Neurol., 1973, 3, 73, (rev, metab, pharmacol)
• Falck, R.L., Drug Intell. Clin. Pharm., 1976, 10, 84, (rev)
• Pinder, R.M. et al., Drugs, 1976, 11, 329, (rev)
• Lotti, V.J. et al., Clin. Ther., 1977, 1, 66, (Sinemet)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 840
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CBQ500