Brompheniramine Maleate

• Catalog No.: Bio-0009
• CAS Number: 86-22-6
• M. F.: C20H23BrN2O4
• M. W.: 435.31162

SYNONYMS

• IUPAC name: (2Z)-but-2-enedioic acid; [(3S)-3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine
• IUPAC Traditional name: (2Z)-but-2-enedioic acid; [(3S)-3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine
• Synonyms: Disomer; Halin; Dexbrompheniramine maleate

DATABASE IDS

• CAS Number: 86-22-6

PROPERTIES

• Application(s): Antihistamine drug
• Application(s): Has antidepressant properties
• Salt Data: Maleate
• Mechanism of Action: Histamine H1 receptor antagonist

REFERENCES

• Saijo, S., Yakugaku Zasshi, 1952, 72, 1529; CA, 47, 8080i, (synth)
• Bruce, R.B. et al., J. Med. Chem., 1968, 11, 1031, (synth, tlc, metab)
• Shafi'ee, A. et al., J. Med. Chem., 1969, 12, 266, (abs config)
• James, M.N.G. et al., J. Med. Chem., 1971, 14, 670, (cryst struct)
• Fricke, F.L., J. Assoc. Off. Anal. Chem., 1972, 55, 1162, (glc)
• Berkoff, C.E. et al., Synth. Commun., 1980, 10, 939, (synth)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 4002
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 932
• Parvez, M. et al., Acta Cryst. C, 1996, 52, 901, (cryst struct, abs config)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, BNE750; DNW759; DXG100