Benazepril hydrochloride

• Catalog No.: Bio-0006
• CAS Number: 86541-74-4
• M. F.: C24H29ClN2O5
• M. W.: 460.95046

SYNONYMS

• IUPAC name: 2-[(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid hydrochloride
• IUPAC Traditional name: 2-[(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid hydrochloride
• Synonyms: Cibacen; Lotensin

DATABASE IDS

• CAS Number: 86541-74-4

PROPERTIES

• Application(s): Antihypertensive agent
• Salt Data: HCl
• Mechanism of Action: Angiotensin-converting enzyme inhibitor

REFERENCES

• Watthey, J.W.H. et al., J. Med. Chem., 1985, 28, 1511, (synth, pharmacol)
• Kaiser, G. et al., J. Chromatogr., 1987, 419, 123, (glc, ms)
• Boyer, S.K. et al., Helv. Chim. Acta, 1988, 71, 337, (synth, ir, pmr)
• Webb, R.L. et al., Cardiovasc. Drug Rev., 1990, 8, 89, (rev)
• Kunick, C., Pharm. Ztg., 1994, 139, 26, (rev)
• ACE Inhibitors: Current Use and Future Prospects, (Ed. Schachter, M.), Martin Dunitz, 1995, (book)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 827