Aripiprazole

• Catalog No.: Bio-0004
• CAS Number: 129722-12-9
• M. F.: C23H27Cl2N3O2
• M. W.: 448.38538

SYNONYMS

• IUPAC name: 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one
• IUPAC Traditional name: 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one

DATABASE IDS

• CAS Number: 129722-12-9

PROPERTIES

• Application(s): Antipsychotic agent
• Mechanism of Action: Shows presynaptic dopamine autoreceptor agonist activity and postsynaptic dopamine D2-receptor antagonist activity

REFERENCES

• Eur. Pat., 1990, Otsuka, 367 141; CA, 113, 152468y, (synth, pharmacol)
• Kikuchi, T. et al., J. Pharmacol. Exp. Ther., 1995, 274, 329-336, (pharmacol)
• Semba, J. et al., Neuropharmacology, 1995, 34, 785-791, (pharmacol)
• Inoue, T. et al., J. Pharmacol. Exp. Ther., 1996, 277, 137-143, (pharmacol)
• Inoue, T. et al., Eur. J. Pharmacol., 1997, 321, 105-111, (pharmacol)
• Yamada, S. et al., J. Pharm. Pharmacol., 1997, 49, 206-208, (pharmacol)
• Morita, S. et al., Tetrahedron, 1998, 54, 4811-4818, (metab)