Alfuzosin

• Catalog No.: Bio-0003
• CAS Number: 81403-80-7
• M. F.: C19H27N5O4
• M. W.: 389.44878

SYNONYMS

• IUPAC name: N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide
• IUPAC Traditional name: N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide
• Synonyms: Urion; Zatral; Alfoten; Mittoral

DATABASE IDS

• CAS Number: 81403-80-7

PROPERTIES

• Application(s): Antihypertensive agent
• Application(s): Used in the treatment of benign prostatic hypertrophy
• Mechanism of Action: alpha 1-Adrenoceptor antagonist

REFERENCES

• U.S. Pat., 1982, Synthelabo, 4 315 007; CA, 96, 162737e, (synth)
• Allen, J., J. Labelled Compd. Radiopharm., 1983, 20, 1283, (synth)
• Scott, M.G. et al., Eur. J. Clin. Pharmacol., 1989, 37, 53, (pharmacokinet)
• Rouchouse, A. et al., J. Chromatogr., 1990, 506, 601, (hplc, enantiomers)
• Lefevre-Borg, F. et al., Br. J. Pharmacol., 1993, 109, 1282, (pharmacol)
• Wilde, M.I. et al., Drugs, 1993, 45, 410, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 342