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Alfuzosin

Catalog No. Bio-0003 Name InterBioScreen
CAS Number 81403-80-7 Website http://www.ibscreen.com
M. F. C19H27N5O4 Telephone +7 49652 40091
M. W. 389.44878 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 230

SYNONYMS

IUPAC name
N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide
IUPAC Traditional name
N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide
Synonyms
Urion
Zatral
Alfoten
Mittoral

DATABASE IDS

CAS Number 81403-80-7

PROPERTIES

Application(s) Antihypertensive agent
Application(s) Used in the treatment of benign prostatic hypertrophy
Mechanism of Action alpha 1-Adrenoceptor antagonist

DETAILS

REFERENCES

  • U.S. Pat., 1982, Synthelabo, 4 315 007; CA, 96, 162737e, (synth)
  • Allen, J., J. Labelled Compd. Radiopharm., 1983, 20, 1283, (synth)
  • Scott, M.G. et al., Eur. J. Clin. Pharmacol., 1989, 37, 53, (pharmacokinet)
  • Rouchouse, A. et al., J. Chromatogr., 1990, 506, 601, (hplc, enantiomers)
  • Lefevre-Borg, F. et al., Br. J. Pharmacol., 1993, 109, 1282, (pharmacol)
  • Wilde, M.I. et al., Drugs, 1993, 45, 410, (rev)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 342