MC 1568_Molecular_structure_CAS_852475-26-4)

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MC 1568
Catalog No.	M199250	Name	Toronto Research Chemicals
CAS Number	852475-26-4	Website	http://www.trc-canada.com
M. F.	C17H15FN2O3	Telephone	+1 (416) 665-9696
M. W.	314.3110032	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 72706

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SYNONYMS

IUPAC name

(2E)-3-{4-[(1E)-3-(3-fluorophenyl)-3-oxoprop-1-en-1-yl]-1-methyl-1H-pyrrol-2-yl}-N-hydroxyprop-2-enamide

IUPAC Traditional name

(2E)-3-{4-[(1E)-3-(3-fluorophenyl)-3-oxoprop-1-en-1-yl]-1-methylpyrrol-2-yl}-N-hydroxyprop-2-enamide

Synonyms

3-[4-(3-(3-Fluorophenyl)-3-oxo-1-propen-1-yl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide

DATABASE IDS

CAS Number

852475-26-4

PROPERTIES

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DETAILS

Description (English)

A selective class II (IIa) histone deacetylase (HDAC II) inhibitor. It exhibits tissue-selective inhibition between members of class II acetylases in vivo, particularly in skeletal muscle and the heart. It arrests myogenesis through the stabilization of m

REFERENCES

Mai, A. et al.: Mol.Pharmacol., 72, 1111 (2007)
Mai, A. et al.: J.Med.Chem., 48, 3344 (2007)
Nebbioso, A. et al.: Eur. Mol. Biol. Org. Rep., 10, 776 (2007)