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2-Isoniazid

Catalog No. I821455 Name Toronto Research Chemicals
CAS Number 1452-63-7 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
pyridine-2-carbohydrazide
IUPAC Traditional name
pyridine-2-carbohydrazide
Synonyms
2-Pyridinecarboxylic Hydrazide
Picolinoyl Hydrazide
Picolinic Hydrazide
Pyridine-2-carbohydrazide
2-Pyridinecarboxylic Acid Hydrazide, Picolinic Acid, 2-(Hydrazinocarbonyl)pyridine
Picolinoylhydrazine

DATABASE IDS

CAS Number 1452-63-7

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
An impurity of Isoniazid (I821450), which is an antibiotic for treatment of Mycobacterium tuberculosis and inhibits mycolic acid biosynthesis. Intermediate used for the synthesis of analogs of antitumor agent 1-acetyl-2-picolinoylhydrazine.

REFERENCES

  • Brewer, G.A., et al.: Anal. Profiles. Drug. Subs., 6, 183 (1977)
  • Weber, W.W., et al.: Clin. Pharmacokinet., 4, 401 (1977)
  • Rutner, H., et al.: Cancer. Chem. Rep., 58, 803 (1974)