NAMES AND DATABASE IDS
NAMES AND DATABASE IDS
Names Database IDs
IUPAC name
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pyridine-2-carbohydrazide
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IUPAC Traditional name
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pyridine-2-carbohydrazide
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Synonyms
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Picolinohydrazide
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Pyridine-2-carboxylic acid hydrazide
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2-Pyridinecarboxylic Acid Hydrazide, Picolinic Acid, 2-(Hydrazinocarbonyl)pyridine
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2-Pyridinecarboxylic Hydrazide
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Picolinic Hydrazide
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Picolinoyl Hydrazide
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Picolinoylhydrazine
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Pyridine-2-carbohydrazide
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2-Isoniazid
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CAS Number
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MDL Number
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PubChem SID
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PubChem CID
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DATA SOURCES
DATA SOURCES
All Sources Commercial Sources Non-commercial Sources
CALCULATED PROPERTIES
CALCULATED PROPERTIES
JChem
Acid pKa
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14.042358
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H Acceptors
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3
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H Donor
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2
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LogD (pH = 5.5)
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-0.30502123
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LogD (pH = 7.4)
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-0.30441946
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Log P
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-0.30441168
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Molar Refractivity
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37.0916 cm3
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Polarizability
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13.714657 Å3
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Polar Surface Area
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68.01 Å2
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Rotatable Bonds
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1
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Lipinski's Rule of Five
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true
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DETAILS
DETAILS
TRC
Toronto Research Chemicals -
I821455
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An impurity of Isoniazid (I821450), which is an antibiotic for treatment of Mycobacterium tuberculosis and inhibits mycolic acid biosynthesis. Intermediate used for the synthesis of analogs of antitumor agent 1-acetyl-2-picolinoylhydrazine. |
REFERENCES
REFERENCES
From Suppliers
Google Scholar
PubMed
Google Books
- • Brewer, G.A., et al.: Anal. Profiles. Drug. Subs., 6, 183 (1977)
- • Weber, W.W., et al.: Clin. Pharmacokinet., 4, 401 (1977)
- • Rutner, H., et al.: Cancer. Chem. Rep., 58, 803 (1974)
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PATENTS
PATENTS
PubChem Patent
Google Patent