Granisetron Hydrochloride_Molecular_structure_CAS_107007-99-8)

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Granisetron Hydrochloride
Catalog No.	G780000	Name	Toronto Research Chemicals
CAS Number	107007-99-8	Website	http://www.trc-canada.com
M. F.	C18H25ClN4O	Telephone	+1 (416) 665-9696
M. W.	348.8703	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage	-20°C Freezer	Chembase ID: 72630

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SYNONYMS

IUPAC name

1-methyl-N-{9-methyl-9-azabicyclo[3.3.1]nonan-3-yl}-1H-indazole-3-carboxamide hydrochloride

IUPAC Traditional name

GRAN hydrochloride

Synonyms

Kytril

BRL-43694A

1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide Hydrochloride

DATABASE IDS

CAS Number

107007-99-8

PROPERTIES

Certificate of Analysis	Download
Apperance	White to Off-White Sold
Melting Point	290-292°C
Solubility	Methanol
Solubility	Water
MSDS Link	Download
Storage Condition	-20°C Freezer

DETAILS

Description (English)

A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the va

REFERENCES

Kilpatrick, G.J., et al.: Nature, 330, 746 (1987)
Durig, T., et al.: J. Pharm. Sci., 86, 1092 (1987)
Yuasa, H., et al.: Chem. Pharm. Bull., 44, 1361 (1987)