2,5-Anhydro-2,5-imino-D-glucitol

• Catalog No.: A648300
• CAS Number: 132295-44-4
• M. F.: C6H13NO4
• M. W.: 163.17172
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (2S,3S,5R)-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diol
• IUPAC Traditional name: (2S,3S,5R)-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diol
• Synonyms: 2,5-Anhydro-2,5-imino-D-glucitol; (2R,3R,4R,5S)-3,4-Dihydroxy-2,5-pyrrolidinedimethanol

DATABASE IDS

• CAS Number: 132295-44-4

PROPERTIES

• Apperance: White Solid
• Melting Point: 139-142°C
• Solubility: Methanol (sparingly)
• Solubility: Water,
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Many pyrrolidines are powerful inhibitors of glycohydrolases, enzymes responsible for cleavage of glycosidic bonds, glycoprotein processing and the gastrointestinal breakdown of dietary carbohydrates. These compounds are charged at physiological pH and

REFERENCES

• Fellows, L.E., et al.: J. Chem. Brit., 287, (1987)
• Elbein, A.D.: Annu. Rev. Biochem., 56, 497 (1987)
• Fleet, G.W., et al.: J. Chem. Brit., 287, (1989) Baxter, E.W., et al.: J. Org. Chem., 59, 3175 (1987)
• Tyms, A.S. et al. Lancet 1025, (1987)
• Spearman,