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Trizma® base

Catalog No. 93440 Name Sigma Aldrich
CAS Number 77-86-1 Website http://www.sigmaaldrich.com
M. F. C4H11NO3 Telephone 1-800-521-8956
M. W. 121.13504 Fax
Purity ≥99.5% Email
Storage Chembase ID: 3404

SYNONYMS

Title
Trizma® 碱
IUPAC name
2-amino-2-(hydroxymethyl)propane-1,3-diol
IUPAC Traditional name
tris buffer
Synonyms
氨基丁三醇
2-Amino-2-(hydroxymethyl)-1,3-propanediol
Tris base
Tris(hydroxymethyl)aminomethane
Trometamol
2-氨基-2-(羟甲基)-1,3-丙二醇
Tris 碱
THAM
三羟甲基氨基甲烷

DATABASE IDS

CAS Number 77-86-1
EC Number 201-064-4
Beilstein Number 741883
PubChem SID 24889887
MDL Number MFCD00004679

PROPERTIES

Description aminopeptidase substrate
Linear Formula NH2C(CH2OH)3
Purity ≥99.5%
Quality certified by BAM, according to ISO 17025
Useful pH Range 7 - 9
pKa 8.1 (25°C)
Boiling Point 219-220 °C/10 mmHg(lit.)
Melting Point 167-172 °C(lit.)
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS TY2900000
Safety Statements 26-36
German water hazard class 2

DETAILS

Description (English)
Analysis Note
Exact concentration, expiry date, traceability and detailed information on certification can be found on the certificate and certification report, included in each package. Content and expiry date on label.
Other Notes
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
Description (简体中文)
Analysis Note
精确浓度、有效期、可溯源性以及详细认证信息,请见每个包装内的证书和认证报告。标签上标明含量和有效期。
Other Notes
所有缓冲液的 pH 值与温度和浓度都有关。对于 Tris 缓冲液,温度每降低 1°C,pH 增加约 0.03 个单位,浓度每稀释 10 倍,pH 降低 0.03-0.05 个单位。 对于精确应用,使用带有玻璃/甘汞复合电极的经仔细校正的 pH 计。
法律信息
Trizma 注册商标 Sigma-Aldrich Co. LLC

REFERENCES