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Sodium selenite

Catalog No. S5261 Name Sigma Aldrich
CAS Number 10102-18-8 Website http://www.sigmaaldrich.com
M. F. Na2O3Se Telephone 1-800-521-8956
M. W. 172.93774 Fax
Purity ≥98% Email
Storage Chembase ID: 102752

SYNONYMS

Title
亚硒酸钠
IUPAC name
disodium selenite
IUPAC Traditional name
disodium selenite

DATABASE IDS

MDL Number MFCD00003489
PubChem SID 24899643
CAS Number 10102-18-8
EC Number 233-267-9

PROPERTIES

Linear Formula Na2SeO3
Product Line BioReagent
Purity ≥98%
Suitability suitable for cell culture
Apperance powder
Melting Point >350 °C(lit.)
GHS Pictograms GHS06
GHS Pictograms GHS09
GHS Signal Word Danger
GHS Hazard statements H300-H317-H331-H411
European Hazard Symbols Highly toxic Highly toxic (T+)
European Hazard Symbols Nature polluting Nature polluting (N)
MSDS Link Download
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P261-P264-P273-P280-P301 + P310-P311
RID/ADR UN 2630 6.1/PG 1
Risk Statements 23-28-31-43-51/53
Safety Statements 28-36/37-45-61
Supplemental Hazard Statements Contact with acids liberates toxic gas.
Hazard Class 6.1
UN Number 2630
Packing Group 1
German water hazard class 2

DETAILS

Description (English)
Application
Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.
Description (简体中文)
Application
Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.

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