disodium selenite

• ChemBase ID: 102752
• Molecular Formular: Na2O3Se
• Molecular Mass: 172.93774
• Monoisotopic Mass: 173.88080342
• SMILES: [Na+].[Na+].[O-][Se](=O)[O-]
• Canonical SMILES: [O-][Se](=O)[O-].[Na+].[Na+]
• InChI: InChI=1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
• InChIKey: BVTBRVFYZUCAKH-UHFFFAOYSA-L

NAMES AND DATABASE IDS

Names

• IUPAC name: disodium selenite
• IUPAC Traditional name: disodium selenite; dipotassium selenit
• Synonyms: SODIUM SELENITE, ANHYDROUS; Selenious Acid Disodium Salt; Disodium selenite; Natriumselenit; SODIUM SELENITE; Sodium selenite, anhydrous; Sodium selenite; Selenious Acid, Disodium; Selenious acid, disodium salt; SODIUM SELENITE, γ-IRRADIATED; 无水亚硒酸钠; 亚硒酸钠

Database IDs

• CAS Number: 10102-18-8
• EC Number: 233-267-9
• MDL Number: MFCD00003489
• Merck Index: 148673
• PubChem SID: 24852838; 24899643; 162090070; 24899827
• PubChem CID: 24934
• CHEBI ID: 48843
• ATC CODE: A12CE02
• CHEMBL: 112302
• Chemspider ID: 23308
• Unique Ingredient Identifier: HIW548RQ3W
• Wikipedia Title: Sodium_selenite

CALCULATED PROPERTIES

• Acid pKa: 1.19897
• H Acceptors: 4
• H Donor: 0
• LogD (pH = 5.5): -3.5574248
• LogD (pH = 7.4): -4.2274547
• Log P: -1.2765
• Molar Refractivity: 17.4436 cm^3
• Polarizability: 3.671146 Å^3
• Polar Surface Area: 63.19 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: 85 g/100 mL (20 °C) in water; Freely soluble in water. Insoluble in alcohol; insoluble in alcohol, ethanol
• Apperance: colourless solid; lyophilized powder; powder; Powder
• Melting Point: >350 °C(lit.); >350°C; 217 deg. C; 710 °C (decomp.)
• Boiling Point: 684 +/- 1 deg. C
• Density: 3.1 g/cm^3
• Vapor Pressure: > 0.001 mm Hg at 20 °C

Safety Information

• Storage Condition: Room Temperature (15-30°C)
• Storage Warning: Hygroscopic
• RTECS: VS7350000
• European Hazard Symbols: Dangerous for the environment (N); Nature polluting (N); Highly toxic (T+); Very toxic (T+)
• UN Number: 2630; UN2630
• German water hazard class: 2
• Hazard Class: 6.1
• Packing Group: 1; I
• Australian Hazchem: 2X
• Risk Statements: 23-28-31-43-51/53; R:23/24-28-33; R23, R28, R31, R43, R51/53
• Safety Statements: 28-36/37-45-61; S:28-45-20/21; S1/2, S28, S36/37, S45, S61
• EU Classification: T5
• EU Hazard Identification Number: 6.1B
• Emergency Response Guidebook(ERG) Number: 151
• TSCA Listed: 是
• EU Index: 034-003-00-3
• GHS Pictograms: GHS06; GHS09
• GHS Signal Word: Danger
• NFPA704:
  

  0

  3

  0
• GHS Hazard statements: H300-H317-H331-H411; H300-H331-H317-H411
• GHS Precautionary statements: P261-P264-P273-P280-P301 + P310-P311; P261-P301+P310-P302+P352-P321-P405-P501A
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges; Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• RID/ADR: UN 2630 6.1/PG 1
• Supplemental Hazard Statements: Contact with acids liberates toxic gas.

Product Information

• Purity: ~98%; ≥90.0%; ≥95.0% (RT); ≥97.0%; ≥98%; 99%; 99% min, typically 99.75% min (metals basis)
• Grade: JIS special grade; SAJ first grade
• Suitability: suitable for cell culture
• Sterility: γ-irradiated
• Loss on Drying: ≤0.5% loss on drying, 200 °C
• Quality Level: PREMIUM
• Product Line: BioReagent; BioXtra
• Linear Formula: Na2SeO3

DETAILS

MP Biomedicals - 02194741

Cell Culture Reagent
Purity: ~98%

MP Biomedicals - 05201657

MP Biomedicals Rare Chemical collection

MP Biomedicals - 02194587

Cell Culture Reagent
γ-Irradiated
Purity: ~98%

MP Biomedicals - 02102928

White to off-white powder.
Purity: ~98%

Sigma Aldrich - S5261

Application
Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.

Sigma Aldrich - 214485

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
More potent than selenomethionine in reducing carcinogenesis.
Packaging
100, 500 g in poly bottle
5 g in glass bottle

Sigma Aldrich - 71950

Packaging
100, 500 g in poly bottle