Cholera Toxin B subunit

• Catalog No.: C1655
• M. F.: C16H13ClF3NO2
• M. W.: 343.7281296

SYNONYMS

• IUPAC name: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxybenzamide
• IUPAC Traditional name: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxybenzamide
• Synonyms: CTB

DATABASE IDS

• MDL Number: MFCD02356522

PROPERTIES

• Compostion: Protein, ~20% Lowry
• Conjugate: FITC conjugate
• Extent of Labeling: ~1.0 mol FITC per mol protein
• Mol. Weight: mol wt ~12 kDa
• Apperance: lyophilized powder
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 20/21/22-36/37/38-52/53
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Analysis Note
Activity measured by ELISA using ganglioside GM1 coated multiwell plates, rabbit anti-cholera toxin B subunit antibodies, and peroxidase-labeled goat anti-rabbit IgG as the second antibody. 50% saturation of binding was achieved with 0.01-1 μg of the cholera toxin B subunit-FITC conjugate per mL.
Physical form
Lyophilized powder containing Tris buffer salts, sodium chloride, sodium EDTA and sodium azide
Biochem/physiol Actions
The cholera toxin B subunit is used for track tracing in neurological research, taking advantage of GM1 ganglioside binding and retrograde transport. Tissue culture cells treated with cholera toxin are not killed and tissues of animals do not become necrotic.

Description (简体中文)

Analysis Note
Activity measured by ELISA using ganglioside GM1 coated multiwell plates, rabbit anti-cholera toxin B subunit antibodies, and peroxidase-labeled goat anti-rabbit IgG as the second antibody. 50% saturation of binding was achieved with 0.01-1 μg of the cholera toxin B subunit-FITC conjugate per mL.
Physical form
Lyophilized powder containing Tris buffer salts, sodium chloride, sodium EDTA and sodium azide
Biochem/physiol Actions
The cholera toxin B subunit is used for track tracing in neurological research, taking advantage of GM1 ganglioside binding and retrograde transport. Tissue culture cells treated with cholera toxin are not killed and tissues of animals do not become necrotic.