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Sunitinib malate

Catalog No. PZ0012 Name Sigma Aldrich
CAS Number 341031-54-7 Website http://www.sigmaaldrich.com
M. F. C26H33FN4O7 Telephone 1-800-521-8956
M. W. 532.5612232 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 72476

SYNONYMS

IUPAC name
(2S)-2-hydroxybutanedioic acid; N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
IUPAC Traditional name
(-)-malic acid; sunitinib
Synonyms
N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt
SU 11248
SU 011248
SU112248

DATABASE IDS

MDL Number MFCD08282795
CAS Number 341031-54-7

PROPERTIES

Empirical Formula (Hill Notation) C22H27FN4O2 · C4H6O5
Purity ≥98% (HPLC)
Apperance powder
Solubility DMSO: >10 mg/mL
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H360-H372
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
GHS Precautionary statements P201-P308 + P313
Risk Statements 61-2-48/25
Safety Statements 53-22-36/37
Storage Temperature room temp
German water hazard class 2

DETAILS

Description (English)
Biochem/physiol Actions
Sunitinib malate is a receptor tyrosine kinase inhibitor, which targets VEGF-R1, VEGF-R2, VEGF-R3, PDGF-Rα, PDGF-Rβ, KIT, FLT3, CSF-1R, and RET. Sunitinib malate is an anticancer drug.
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Description (简体中文)
Biochem/physiol Actions
Sunitinib malate is a receptor tyrosine kinase inhibitor, which targets VEGF-R1, VEGF-R2, VEGF-R3, PDGF-Rα, PDGF-Rβ, KIT, FLT3, CSF-1R, and RET. Sunitinib malate is an anticancer drug.
Legal Information
Sold for research purposes under agreement from Pfizer Inc.

REFERENCES