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Trizma® base

Catalog No. T1410 Name Sigma Aldrich
CAS Number 77-86-1 Website http://www.sigmaaldrich.com
M. F. C4H11NO3 Telephone 1-800-521-8956
M. W. 121.13504 Fax
Purity ≥99.9% (titration) Email
Storage Chembase ID: 3404

SYNONYMS

Title
Trizma® 碱
IUPAC name
2-amino-2-(hydroxymethyl)propane-1,3-diol
IUPAC Traditional name
tris buffer
Synonyms
氨基丁三醇
2-Amino-2-(hydroxymethyl)-1,3-propanediol
Tris base
Tris(hydroxymethyl)aminomethane
Trometamol
2-氨基-2-(羟甲基)-1,3-丙二醇
Tris 碱
THAM
三羟甲基氨基甲烷

DATABASE IDS

CAS Number 77-86-1
EC Number 201-064-4
Beilstein Number 741883
MDL Number MFCD00004679

PROPERTIES

abs. A40%/290 ≤0.05
Cation Traces heavy metals (as Pb): ≤2 ppm
Description aminopeptidase substrate
Impurities ≤0.2% water (Karl Fischer)
Linear Formula NH2C(CH2OH)3
pH Range 7.0 - 9.2
Purity ≥99.9% (titration)
Suitability cell culture tested
Useful pH Range 7 - 9
pKa 8.1 (25°C)
Apperance white crystalline
Boiling Point 219-220 °C/10 mmHg(lit.)
Melting Point 167-172 °C(lit.)
Solubility : soluble40 % (w/w), clear, colorless
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS TY2900000
Safety Statements 26-36
German water hazard class 2

DETAILS

Description (English)
Other Notes
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Trizma is a registered trademark of Sigma-Aldrich Co. LLC
Description (简体中文)
Other Notes
所有缓冲液的 pH 值与温度和浓度都有关。对于 Tris 缓冲液,温度每降低 1°C,pH 增加约 0.03 个单位,浓度每稀释 10 倍,pH 降低 0.03-0.05 个单位。 对于精确应用,使用带有玻璃/甘汞复合电极的经仔细校正的 pH 计。
法律信息
Trizma 注册商标 Sigma-Aldrich Co. LLC

REFERENCES