β-Glycerophosphate disodium salt hydrate

• Catalog No.: G5422
• CAS Number: 154804-51-0
• M. F.: C3H9Na2O7P
• M. W.: 234.052661

SYNONYMS

• Title: β-甘油磷酸 二钠盐 水合物
• IUPAC name: disodium 2-(phosphonatooxy)propane-1,3-diol hydrate
• IUPAC Traditional name: disodium glycerol 2-phosphate hydrate
• Synonyms: BGP; Glycerol 2-phosphate disodium salt hydrate; 甘油-2-磷酸 二钠盐 水合物

DATABASE IDS

• EC Number: 212-464-3
• MDL Number: MFCD00149082
• CAS Number: 154804-51-0

PROPERTIES

• Biological Source: from synthetic
• Impurities: ≤0.1% Inorganic phosphorus
• Impurities: ≤1.0 mol % L-α-isomer
• Linear Formula: (HOCH2)2CHOP(O)(ONa)2 · xH2O
• Melting Point: 102-104 °C(lit.)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: UA0600000
• German water hazard class: 3

DETAILS

Description (English)

Quality
Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates.9
Application
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.1 BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition.2,3 It functions as an organic phosphate donor4 and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells.5,6 BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.7,8
β-glycerophosphate is used in homegenization solutions for muscles extracts following fixation.
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.

Description (简体中文)

Quality
Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates.9
Application
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.1 BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition.2,3 It functions as an organic phosphate donor4 and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells.5,6 BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.7,8
β-glycerophosphate is used in homegenization solutions for muscles extracts following fixation.
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.