Spermine tetrahydrochloride

• Catalog No.: S1141
• CAS Number: 306-67-2
• M. F.: C10H30Cl4N4
• M. W.: 348.184

SYNONYMS

• Title: 精胺 四盐酸盐
• IUPAC name: (3-aminopropyl)({4-[(3-aminopropyl)amino]butyl})amine tetrahydrochloride
• IUPAC Traditional name: spermine tetrahydrochloride
• Synonyms: N,N′-双(3-氨丙基)-1,4-丁二胺 四盐酸盐

DATABASE IDS

• MDL Number: MFCD00012914
• CAS Number: 306-67-2
• PubChem SID: 24899462
• Beilstein Number: 3911771
• EC Number: 206-189-8

PROPERTIES

• Foreign Activity: DNase, RNase, protease, NICKase, none detected
• Grade: for molecular biology
• Melting Point: 310-311 °C (dec.)(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 36/38
• RTECS: EJ7230000
• Safety Statements: 26-36
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (简体中文)

Application
用于从低盐缓冲液中沉淀 DNA。1
Biochem/physiol Actions
多胺位点混合型 NMDA 激动-拮抗剂。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
多胺位点混合型 NMDA 激动-拮抗剂。在高浓度 (1mM) 下观察到神经保护作用，而在低浓度下则观察到神经毒性。它在番木鳖碱-不敏感性甘氨酸位点能够增强激动剂效应。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。