Genistein

• Catalog No.: G6649
• CAS Number: 446-72-0
• M. F.: C15H10O5
• M. W.: 270.2369
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
• IUPAC Traditional name: genistein
• Synonyms: 4′,5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

DATABASE IDS

• MDL Number: MFCD00016952
• PubChem SID: 24278036
• Beilstein Number: 263823
• CAS Number: 446-72-0
• EC Number: 207-174-9

PROPERTIES

• Biological Source: synthetic
• Purity: ≥98% (HPLC)
• Gene Information: human ... AKT1(207), CYP19A1(1588), EGFR(1956), ESR1(2099), ESR2(2100)mouse ... Esr1(13982), Hexa(15211)rat ... Adora1(29290), Adora2a(25369), Ar(24208)
• Apperance: off-white powder
• Solubility: DMSO: soluble
• Solubility: ethanol: soluble
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: NR2392000
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibitor of tyrosine protein kinase; competitive inhibitor of ATP in other protein kinase reactions. Antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis.