Chembase list of 866358 unique molecular structures

[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]methanamine

$$$$ Data

M. F.

C12H10F3NS

Suppliers	Catalog Number
Apollo Scientific	PC103655

Database	Data ID
PubChem	26985239

M. W.

257.2747096

CAS

Similarity

N/A

ID: 93702

4-phenyl-5-(trifluoromethyl)thiophene-2-carbaldehyde

$$$$ Data

M. F.

C12H7F3OS

Suppliers	Catalog Number
Apollo Scientific	PC103661
A&J Pharmtech	AJA-O28932

Database	Data ID
PubChem	26985236

M. W.

256.2435896

CAS

Similarity

N/A

ID: 93703

6,8-difluoro-4-(piperazin-1-yl)-2-(trifluoromethyl)quinoline

$$$$ Data

M. F.

C14H12F5N3

Suppliers	Catalog Number
Apollo Scientific	PC103667

Database	Data ID
PubChem	26985243

M. W.

317.257196

CAS

Similarity

N/A

ID: 93704

6,8-dichloro-4-(piperazin-1-yl)-2-(trifluoromethyl)quinoline

$$$$ Data

M. F.

C14H12Cl2F3N3

Suppliers	Catalog Number
Apollo Scientific	PC103668

Database	Data ID
PubChem	26985245

M. W.

350.1663896

CAS

Similarity

N/A

ID: 93705

4-(1,4-diazepan-1-yl)-6,8-difluoro-2-(trifluoromethyl)quinoline

$$$$ Data

M. F.

C15H14F5N3

Suppliers	Catalog Number
Apollo Scientific	PC103669

Database	Data ID
PubChem	26985248

M. W.

331.283776

CAS

Similarity

N/A

ID: 93706

6,8-dichloro-4-(1,4-diazepan-1-yl)-2-(trifluoromethyl)quinoline

$$$$ Data

M. F.

C15H14Cl2F3N3

Suppliers	Catalog Number
Apollo Scientific	PC103670

Database	Data ID
PubChem	26985251

M. W.

364.1929696

CAS

Similarity

N/A

ID: 93707

2-{[3-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetic acid

$$$$ Data

M. F.

C8H6F3NO2S

Suppliers	Catalog Number
Apollo Scientific	PC103682

Database	Data ID
PubChem	3755251

M. W.

237.1989496

CAS

Similarity

N/A

ID: 93708

2-{[5-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetic acid

$$$$ Data

M. F.

C8H6F3NO2S

Suppliers	Catalog Number
Apollo Scientific	PC103683
Enamine	EN300-12178

Database	Data ID
PubChem	706722

M. W.

237.1989496

CAS

Similarity

N/A

ID: 93709

4-(trifluoromethyl)pyridine-2-thiol

$$$$ Data

M. F.

C6H4F3NS

Suppliers	Catalog Number
Apollo Scientific	PC103684

Database	Data ID
PubChem	15896766

M. W.

179.1628696

CAS

Similarity

N/A

ID: 93710

1-[3-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid

$$$$ Data

M. F.

C12H13F3N2O2

Suppliers	Catalog Number
Apollo Scientific	PC103685

Database	Data ID
PubChem	11288815

M. W.

274.2390296

CAS

Similarity

N/A

ID: 93711

2-{[8-(trifluoromethyl)quinolin-4-yl]sulfanyl}acetic acid

$$$$ Data

M. F.

C12H8F3NO2S

Suppliers	Catalog Number
Apollo Scientific	PC103686

Database	Data ID
PubChem	33778941

M. W.

287.2576296

CAS

Similarity

N/A

ID: 93712

2-{[2-(trifluoromethyl)quinolin-4-yl]amino}ethan-1-ol

$$$$ Data

M. F.

C12H11F3N2O

Suppliers	Catalog Number
Apollo Scientific	PC103687

Database	Data ID
PubChem	45933592

M. W.

256.2237496

CAS

Similarity

N/A

ID: 93713

4-hydrazinyl-5,7-bis(trifluoromethyl)quinoline

$$$$ Data

M. F.

C11H7F6N3

Suppliers	Catalog Number
Apollo Scientific	PC103688

Database	Data ID
PubChem	45933593

M. W.

295.1837992

CAS

Similarity

N/A

ID: 93714

2-(trifluoromethyl)quinolin-4-amine

$$$$ Data

M. F.

C10H7F3N2

Suppliers	Catalog Number
Apollo Scientific	PC103689

Database	Data ID
PubChem	12554753

M. W.

212.1711896

CAS

1700-93-2

Similarity

N/A

ID: 93715

2-{[6-(trifluoromethyl)quinolin-4-yl]sulfanyl}acetic acid

$$$$ Data

M. F.

C12H8F3NO2S

Suppliers	Catalog Number
Apollo Scientific	PC103690

Database	Data ID
PubChem	45933594

M. W.

287.2576296

CAS

Similarity

N/A

ID: 93716

4-[(2-aminoethyl)sulfanyl]-8-(trifluoromethyl)quinoline

$$$$ Data

M. F.

C12H11F3N2S

Suppliers	Catalog Number
Apollo Scientific	PC103691

Database	Data ID
PubChem	45933595

M. W.

272.2893496

CAS

Similarity

N/A

ID: 93717

4-hydrazinyl-6-(trifluoromethyl)quinoline

$$$$ Data

M. F.

C10H8F3N3

Suppliers	Catalog Number
Apollo Scientific	PC103692
InterBioScreen	BB_SC-8528

Database	Data ID
PubChem	17039908

M. W.

227.1858296

CAS

Similarity

N/A

ID: 93718

5,7-bis(trifluoromethyl)quinolin-4-amine

$$$$ Data

M. F.

C11H6F6N2

Suppliers	Catalog Number
Apollo Scientific	PC103693

Database	Data ID
PubChem	45933596

M. W.

280.1691592

CAS

Similarity

N/A

ID: 93719

2-{[6-(trifluoromethyl)quinolin-4-yl]amino}ethane-1-thiol

$$$$ Data

M. F.

C12H11F3N2S

Suppliers	Catalog Number
Apollo Scientific	PC103694

Database	Data ID
PubChem	45933597

M. W.

272.2893496

CAS

Similarity

N/A

ID: 93720

2-(trifluoromethyl)quinoline-4-thiol

$$$$ Data

M. F.

C10H6F3NS

Suppliers	Catalog Number
Apollo Scientific	PC103695

Database	Data ID
PubChem	18526364

M. W.

229.2215496

CAS

Similarity

N/A

ID: 93721

4-[(2-aminoethyl)sulfanyl]-6-(trifluoromethyl)quinoline

$$$$ Data

M. F.

C12H11F3N2S

Suppliers	Catalog Number
Apollo Scientific	PC103696

Database	Data ID
PubChem	45933598

M. W.

272.2893496

CAS

Similarity

N/A

ID: 93722

2-{[6-(trifluoromethyl)quinolin-4-yl]amino}ethan-1-ol

$$$$ Data

M. F.

C12H11F3N2O

Suppliers	Catalog Number
Apollo Scientific	PC103698

Database	Data ID
PubChem	45933599

M. W.

256.2237496

CAS

Similarity

N/A

ID: 93723

2-{[8-(trifluoromethyl)quinolin-4-yl]amino}ethane-1-thiol

$$$$ Data

M. F.

C12H11F3N2S

Suppliers	Catalog Number
Apollo Scientific	PC103699

Database	Data ID
PubChem	45933600

M. W.

272.2893496

CAS

Similarity

N/A

ID: 93724

2-{[8-(trifluoromethyl)quinolin-4-yl]amino}ethan-1-ol

$$$$ Data

M. F.

C12H11F3N2O

Suppliers	Catalog Number
Apollo Scientific	PC103701

Database	Data ID
PubChem	45933601

M. W.

256.2237496

CAS

Similarity

N/A

ID: 93725

2-{[2-(trifluoromethyl)quinolin-4-yl]amino}ethane-1-thiol

$$$$ Data

M. F.

C12H11F3N2S

Suppliers	Catalog Number
Apollo Scientific	PC103702

Database	Data ID
PubChem	45933602

M. W.

272.2893496

CAS

Similarity

N/A

ID: 93726

5,7-bis(trifluoromethyl)quinoline-4-thiol

$$$$ Data

M. F.

C11H5F6NS

Suppliers	Catalog Number
Apollo Scientific	PC103704

Database	Data ID
PubChem	45933603

M. W.

297.2195192

CAS

Similarity

N/A

ID: 93727

2-(2,2,2-trifluoroethoxy)pyridine-3-carboxylic acid

$$$$ Data

M. F.

C8H6F3NO3

Suppliers	Catalog Number
Apollo Scientific	PC103705
Enamine	EN300-31779

Database	Data ID
PubChem	15267492

M. W.

221.1333496

CAS

Similarity

N/A

ID: 93728

ethyl 5-fluoro-2-hydroxybenzoate

$$$$ Data

M. F.

C9H9FO3

Suppliers	Catalog Number
Apollo Scientific	PC10376

Database	Data ID
PubChem	2783185

M. W.

184.1643632

CAS

Similarity

N/A

ID: 93729

methyl 5-fluoro-2-hydroxybenzoate

$$$$ Data

M. F.

C8H7FO3

Suppliers	Catalog Number
Sigma Aldrich	554081
Apollo Scientific	PC10377

Database	Data ID
PubChem	2783186

M. W.

170.1377832

CAS

391-92-4

Similarity

N/A

ID: 93730

(3,5-difluoro-2-methoxyphenyl)boronic acid

$$$$ Data

M. F.

C7H7BF2O3

Suppliers	Catalog Number
Alfa Aesar	L19773
Apollo Scientific	PC10378
A&J Pharmtech	AJA-O34602

Database	Data ID
PubChem	2734607

M. W.

187.9364864

CAS

737000-76-9

Similarity

N/A

ID: 93731

[3-fluoro-4-(trifluoromethoxy)phenyl]boronic acid

$$$$ Data

M. F.

C7H5BF4O3

Suppliers	Catalog Number
Apollo Scientific	PC10382
A&J Pharmtech	AJA-O29436

Database	Data ID
PubChem	2783193

M. W.

223.9174128

CAS

187804-79-1

Similarity

N/A

ID: 93732

3-chloro-4-fluorobenzene-1-carbothioamide

$$$$ Data

M. F.

C7H5ClFNS

Suppliers	Catalog Number
Alfa Aesar	L11132
Apollo Scientific	PC10385

Database	Data ID
PubChem	2779521

M. W.

189.6377032

CAS

130560-97-3

Similarity

N/A

ID: 93733

4-(2-fluorobenzoyl)phenol

$$$$ Data

M. F.

C13H9FO2

Suppliers	Catalog Number
Alfa Aesar	L15494
Apollo Scientific	PC10389

Database	Data ID
PubChem	2783235

M. W.

216.2077632

CAS

101969-75-9

Similarity

N/A

ID: 93734

(2-fluorophenyl)(4-methoxyphenyl)methanone

$$$$ Data

M. F.

C14H11FO2

Suppliers	Catalog Number
Alfa Aesar	L13653
Apollo Scientific	PC10390

Database	Data ID
PubChem	2783236

M. W.

230.2343432

CAS

66938-29-2

Similarity

N/A

ID: 93735

1-fluoro-3-isothiocyanatobenzene

$$$$ Data

M. F.

C7H4FNS

Suppliers	Catalog Number
Sigma Aldrich	F14351
Alfa Aesar	B25001
Apollo Scientific	PC10393

Database	Data ID
PubChem	9834

M. W.

153.1767632

CAS

404-72-8

Similarity

N/A

ID: 93736

2,2,2-trifluoro-1-(thiophen-2-yl)ethan-1-one

$$$$ Data More

M. F.

C6H3F3OS

Suppliers	Catalog Number
Sigma Aldrich	422215
Alfa Aesar	L12585
Apollo Scientific	PC10396

Database	Data ID
PubChem	136464

M. W.

180.1476296

CAS

651-70-7

Similarity

N/A

ID: 93737

2-fluoro-6-iodoaniline

$$$$ Data

M. F.

C6H5FIN

Suppliers	Catalog Number
Apollo Scientific	PC10400
Bide Pharmatech	BD75050

Database	Data ID
PubChem	2783156

M. W.

237.0134732

CAS

886762-73-8

Similarity

N/A

ID: 93738

4-bromo-3-fluoro-2-nitroaniline

$$$$ Data

M. F.

C6H4BrFN2O2

Suppliers	Catalog Number
Apollo Scientific	PC10401

Database	Data ID
PubChem	2783158

M. W.

235.0105632

CAS

886762-75-0

Similarity

N/A

ID: 93739

4-bromo-3-fluorobenzene-1,2-diamine

$$$$ Data

M. F.

C6H6BrFN2

Suppliers	Catalog Number
Apollo Scientific	PC10402

Database	Data ID
PubChem	2783203

M. W.

205.0276432

CAS

886762-86-3

Similarity

N/A

ID: 93740

diethylamine; trifluoro(sulfonyl)methane

$$$$ Data

M. F.

C5H11F3NO2S

Suppliers	Catalog Number
Apollo Scientific	PC10403

Database	Data ID
PubChem	44717305

M. W.

206.2065496

CAS

60933-18-8

Similarity

N/A

ID: 93741

1,1-difluorocyclopentane

$$$$ Data

M. F.

C5H8F2

Suppliers	Catalog Number
Apollo Scientific	PC10404

Database	Data ID
PubChem	2783162

M. W.

106.1138264

CAS

1120-70-3

Similarity

N/A

ID: 93742

1,1,2,3,3-pentafluoro-3-(trifluoromethoxy)prop-1-ene

$$$$ Data

M. F.

C4F8O

Suppliers	Catalog Number
Apollo Scientific	PC10405

Database	Data ID
PubChem	2783163

M. W.

216.0294256

CAS

67641-44-5

Similarity

N/A

ID: 93743

3,5-bis(trifluoromethyl)benzene-1-sulfonamide

$$$$ Data

M. F.

C8H5F6NO2S

Suppliers	Catalog Number
Apollo Scientific	PC10406

Database	Data ID
PubChem	2783165

M. W.

293.1862192

CAS

Similarity

N/A

ID: 93744

2-bromo-1-(3,4,5-trifluorophenyl)ethan-1-one

$$$$ Data

M. F.

C8H4BrF3O

Suppliers	Catalog Number
Apollo Scientific	PC10407

Database	Data ID
PubChem	2783166

M. W.

253.0159696

CAS

Similarity

N/A

ID: 93745

2-bromo-1-(2,3-difluorophenyl)ethan-1-one

$$$$ Data

M. F.

C8H5BrF2O

Suppliers	Catalog Number
Apollo Scientific	PC10408

Database	Data ID
PubChem	2783167

M. W.

235.0255064

CAS

886762-77-2

Similarity

N/A

ID: 93746

3-(4-fluorophenyl)-3-oxopropanenitrile

$$$$ Data More

M. F.

C9H6FNO

Suppliers	Catalog Number
Sigma Aldrich	681822
Apollo Scientific	PC10409
Chemik	CHB09109

Database	Data ID
PubChem	2783172

M. W.

163.1484432

CAS

4640-67-9

Similarity

N/A

ID: 93747

3-(4-fluorophenyl)prop-2-enenitrile

$$$$ Data

M. F.

C9H6FN

Suppliers	Catalog Number
Apollo Scientific	PC10410

Database	Data ID
PubChem	5372942

M. W.

147.1490432

CAS

24654-48-6

Similarity

N/A

ID: 93748

2-{[2-nitro-4-(trifluoromethyl)phenyl]sulfanyl}aniline

$$$$ Data

M. F.

C13H9F3N2O2S

Suppliers	Catalog Number
Apollo Scientific	PC10412

Database	Data ID
PubChem	345425

M. W.

314.2829696

CAS

Similarity

N/A

ID: 93749

2-bromo-1-(2,4,5-trifluorophenyl)ethan-1-one

$$$$ Data

M. F.

C8H4BrF3O

Suppliers	Catalog Number
Apollo Scientific	PC10423

Database	Data ID
PubChem	2783181

M. W.

253.0159696

CAS

Similarity

N/A

ID: 93750

2-bromo-1-(2,4,6-trifluorophenyl)ethan-1-one

$$$$ Data

M. F.

C8H4BrF3O

Suppliers	Catalog Number
Apollo Scientific	PC10424

Database	Data ID
PubChem	2783182

M. W.

253.0159696

CAS

746630-36-4

Similarity

N/A

Part I: Carbon
- I.1: Carbon-Carbon Bonds
- I.1.1 Alkanes
- Primary carbon
- Secondary carbon
- Tertiary carbon
- Quaternary carbon
- I.1.2 C-C double and Triple Bonds
- Alkene
- Alkyne
- Allene
- I.2: One Carbon-Hetero Bond
- I.2.1 Alkyl Halogenides
- Alkylchloride
- Alkylfluoride
- Alkylbromide
- Alkyliodide
- I.2.2 Alcohols and Ethers
- Alcohol
- Primary alcohol
- Secondary alcohol
- Tertiary alcohol
- Dialkylether
- Dialkylthioether
- Alkylarylether
- Diarylether
- Alkylarylthioether
- Diarylthioether
- Oxonium
- I.2.3 Amines
- Amine
- Primary aliphatic amine
- Secondary aliphatic amine
- Tertiary aliphatic amine
- Quaternary aliphatic ammonium
- Primary aromatic amine
- Secondary aromatic amine
- Tertiary aromatic amine
- Quaternary aromatic ammonium
- Secondary mixed amine
- Tertiary mixed amine
- Quaternary mixed ammonium
- Ammonium
- I.2.4 Others
- Alkylthiol
- Dialkylthioether
- Alkylarylthioether
- Disulfide
- 1,2-Aminoalcohol
- 1,2-Diol
- 1,1-Diol
- Hydroperoxide
- Peroxo
- Organolithium compounds
- Organomagnesium compounds
- Organometallic compounds
- I.3: Two Carbon-Hetero Bonds (Carbonyl and Derivatives)
- I.3.1 Double Bond to Hetero
- Aldehyde
- Ketone
- Thioaldehyde
- Thioketone
- Imine
- Immonium
- Oxime
- Oximether
- I.3.2. Two Single Bonds to Hetero
- Acetal
- Hemiacetal
- Aminal
- Hemiaminal
- Thioacetal
- Thiohemiacetal
- Halogen acetal like
- Acetal like
- Halogenmethylen ester and similar
- NOS methylen ester and similar
- Hetero methylen ester and similar
- Cyanhydrine
- I.3.3 Single Bond to Hetero, C=C Double Bond (Enols and Similar)
- Chloroalkene
- Fluoroalkene
- Bromoalkene
- Iodoalkene
- Enol
- Endiol
- Enolether
- Enolester
- Enamine
- Thioenol
- Thioenolether
- I.4: Three Carbon-Hetero Bonds (Carboxyl and Derivatives)
- Acylchloride
- Acylfluoride
- Acylbromide
- Acyliodide
- Acylhalide
- Carboxylic acid
- Carboxylic ester
- Lactone
- Carboxylic anhydride
- Carboxylic acid derivative
- Carbothioic acid
- Carbothioic S ester
- Carbothioic S lactone
- Carbothioic O ester
- Carbothioic O lactone
- Carbothioic halide
- Carbodithioic acid
- Carbodithioic ester
- Carbodithiolactone
- Amide
- Primary amide
- Secondary amide
- Tertiary amide
- Lactam
- Alkyl imide
- N hetero imide
- Imide acidic
- Thioamide
- Thiolactam
- Oximester
- Amidine
- Hydroxamic acid
- Hydroxamic acid ester
- Imidoacid
- Imidoacid cyclic
- Imidoester
- Imidolactone
- Imidothioacid
- Imidothioacid cyclic
- Imidothioester
- Imidothiolactone
- Amidine
- Imidolactam
- Imidoylhalide
- Imidoylhalide cyclic
- Amidrazone
- Alpha aminoacid
- Alpha hydroxyacid
- Peptide middle
- Peptide C term
- Peptide N term
- Carboxylic orthoester
- Ketene
- Ketenacetal
- Nitrile
- Isonitrile
- Vinylogous carbonyl or carboxyl derivative
- Vinylogous acid
- Vinylogous ester
- Vinylogous amide
- Vinylogous halide
- I.5: Four Carbon-Hetero Bonds (Carbonic Acid and Derivatives)
- Carbonic acid dieester
- Carbonic acid esterhalide
- Carbonic acid monoester
- Carbonic acid derivatives
- Thiocarbonic acid dieester
- Thiocarbonic acid esterhalide
- Thiocarbonic acid monoester
- Urea
- Thiourea
- Isourea
- Isothiourea
- Guanidine
- Carbaminic acid
- Urethan(Carbamate ester)
- Biuret
- Semicarbazide
- Carbazide
- Semicarbazone
- Carbazone
- Thiosemicarbazide
- Thiocarbazide
- Thiosemicarbazone
- Thiocarbazone
- Isocyanate
- Cyanate
- Isothiocyanate
- Thiocyanate
- Carbodiimide
- Orthocarbonic derivatives
- I.6 Aromatics
- Phenol
- 1,2-Diphenol
- Arylchloride
- Arylfluoride
- Arylbromide
- Aryliodide
- Arylthiol
- Iminoarene
- Oxoarene
- Thioarene
- Hetero N basic H
- Hetero N basic no H
- Hetero N nonbasic
- Hetero O
- Hetero S
- Heteroaromatic
Part II: N, S, P, Si, B
- II.1 Nitrogen
- Nitrite
- Thionitrite
- Nitrate
- Nitro
- Nitroso
- Azide
- Acylazide
- Diazo
- Diazonium
- Nitrosamine
- Nitrosamide
- N-Oxide
- Hydrazine
- Hydrazone
- Hydroxylamine
- II.2 Sulfur
- Sulfon
- Sulfoxide
- Sulfonium
- Sulfuric acid
- Sulfuric monoester
- Sulfuric diester
- Sulfuric monoamide
- Sulfuric diamide
- Sulfuric esteramide
- Sulfuric derivative
- Sulfonic acid
- Sulfonamide
- Sulfonic ester
- Sulfonic halide
- Sulfonic derivative
- Sulfinic acid
- Sulfinic amide
- Sulfinic ester
- Sulfinic halide
- Sulfinic derivative
- Sulfenic acid
- Sulfenic amide
- Sulfenic ester
- Sulfenic halide
- Sulfenic derivative
- II.3 Phosphorous
- Phosphine
- Phosphine oxide
- Phosphonium
- Phosphorylen
- Phosphonic acid
- Phosphonic monoester
- Phosphonic diester
- Phosphonic monoamide
- Phosphonic diamide
- Phosphonic esteramide
- Phosphonic acid derivative
- Phosphoric acid
- Phosphoric monoester
- Phosphoric diester
- Phosphoric triester
- Phosphoric monoamide
- Phosphoric diamide
- Phosphoric triamide
- Phosphoric monoestermonoamide
- Phosphoric diestermonoamide
- Phosphoric monoesterdiamide
- Phosphoric acid derivative
- Phosphinic acid
- Phosphinic ester
- Phosphinic amide
- Phosphinic acid derivative
- Phosphonous acid
- Phosphonous monoester
- Phosphonous diester
- Phosphonous monoamide
- Phosphonous diamide
- Phosphonous esteramide
- Phosphonous derivatives
- Phosphinous acid
- Phosphinous ester
- Phosphinous amide
- Phosphinous derivatives
- II.4 Silicon
- Quart silane
- Non-quart silane
- Silylmonohalide
- Het trialkylsilane
- Dihet dialkylsilane
- Trihet alkylsilane
- Silicic acid derivative
- II.5 Boron
- Trialkylborane
- Boric acid derivatives
- Boronic acid derivative
- Borohydride
- Quaternary boron
Part III: Some Special Patterns
- III.1 Chains
- III.2 Rings
- Aromatic
- Heterocyclic
- Epoxide
- NH aziridine
- Spiro
- Annelated rings
- Bridged rings
- III.3 Sugars and Nucleosides/Nucleotides, Steroids
- Sugar pattern 1
- Sugar pattern 2
- Sugar pattern combi
- Sugar pattern 2 reducing
- Sugar pattern 2 alpha
- Sugar pattern 2 beta
- III.4 Everything else...
- Conjugated double bond
- Conjugated tripple bond
- Cis double bond
- Trans double bond
- Mixed anhydrides
- Halogen on hetero
- Halogen multi subst
- Trifluoromethyl
- C ONS bond
- Charged
- Anion
- Kation
- Salt
- 1,3-Tautomerizable
- 1,5-Tautomerizable
- Rotatable bond
- Michael acceptor
- Dicarbodiazene
- CH-acidic
- CH-acidic strong
- Chiral center specified