quinolin-8-ol

• ChemBase ID: 85390
• Molecular Formular: C9H7NO
• Molecular Mass: 145.15798
• Monoisotopic Mass: 145.05276385
• SMILES: n1cccc2cccc(c12)O
• Canonical SMILES: Oc1cccc2c1nccc2
• InChI: InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H
• InChIKey: MCJGNVYPOGVAJF-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: quinolin-8-ol
• IUPAC Traditional name: 8 hydroxyquinoline
• Synonyms: 8-Hydroxychinolin; 8-Oxyquinoline; 8-Quinol; AQ+; Albisal; Fennosan H 30; Oxin; Oxoquinoline; Oxychinolin; Oxyquinoline; Phenopyridine; Tumex; NSC 2039; NSC 285166; NSC 402623; NSC 48037; NSC 54230; NSC 615011; NSC 82404; NSC 82405; NSC 82409; NSC 82410; NSC 82412; quinolin-8-ol; 1-azanaphthalene-8-ol; Fennosan H 30, hydroxybenzopyridinl; hoxybenzopyridinl; oxychinolil; oxyquinolinl; phenopyridinl; quinophenol; Quinolin-8-ol; 8-Hydroxyquinoline; 8-Hydroxyquinoline; 8-Oxychinolin; Oxine; 8-QUINOLINOL; 8-QUINOLINOL, ACS; 8-QUINOLINOL; 8-Hydroxyquinoline; 8-Quinolinol; 8-Hydroxyquinoline, ACS; 8-氢氧化喹啉; 8-羟基喹啉; 8-羟基氮杂萘; 喔星; 8-羟基喹啉; 8-羟基喹啉, ACS

Database IDs

• CAS Number: 148-24-3
• EC Number: 205-711-1
• MDL Number: MFCD00006807
• Beilstein Number: 114512
• Merck Index: 144843
• PubChem SID: 24862497; 24859483; 24853168; 162072506; 24855220; 24898938; 24895771; 24879139
• PubChem CID: 1923
• CHEBI ID: 48981
• ATC CODE: G01AC30; A01AB07; D08AH03; R02AA14
• CHEMBL: 310555
• Chemspider ID: 1847
• KEGG ID: D05321
• Unique Ingredient Identifier: 5UTX5635HP
• Wikipedia Title: 8-Hydroxyquinoline

CALCULATED PROPERTIES

• Acid pKa: 9.3576975
• H Acceptors: 2
• H Donor: 1
• LogD (pH = 5.5): 1.7469306
• LogD (pH = 7.4): 1.8207314
• Log P: 1.8273351
• Molar Refractivity: 41.9602 cm^3
• Polarizability: 17.599808 Å^3
• Polar Surface Area: 33.12 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: Almost insoluble in water and diethyl ether. Highly soluble in ethanol, acetone, chloroform, and benzene.; Chloroform
• Apperance: crystalline; Granular; Pale Pale Yellow Solid; White crystalline needles
• Melting Point: 55-58°C; 70-73 °C(lit.); 70-74 °C; 70-76 °C; 70-76°C; 72 - 74°C; 72°C; 72.5-74 °C; 72.5-75 °C; 72-74 °C; 72-74°C; 72-74°C; 72-76°C; 76°C
• Boiling Point: 266.6 °C @ 752 mm; 267 °C/752 mmHg(lit.); 267°C; 267°C/252mm; 267°C; 276°C
• Density: 1.03; 1.034 g/cm^3
• Hydrophobicity(logP): 2.077

Safety Information

• Storage Condition: Refrigerator, Under Inert Atmosphere; Room Temperature (15-30°C), Protect from light
• Storage Warning: Harmful/Irritant/Mutagenic/Light Sensitive/Air Sensitive/Store under Argon; Light Sensitive
• RTECS: VC4200000
• European Hazard Symbols: X; Harmful (Xn)
• German water hazard class: 3
• Risk Statements: 22; 22-68; R:22
• Safety Statements: 36/37; 9-36/37; S:36/37/39
• TSCA Listed: 是
• GHS Pictograms: GHS07; GHS08
• GHS Signal Word: Warning
• Main Hazard: flammable
• GHS Hazard statements: H302; H341-H302
• GHS Precautionary statements: P281-P264-P301+P312-P308+P313-P405-P501A
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Product Information

• Purity: ≥99%; ≥95.0% (NT); ≥99%; ≥99% (perchloric acid titration); ≥99.0%; ≥99.0% (NT); 95%; 97%; 98%; 99%
• Grade: ACS; ACS reagent; ACS reagent, reag. Ph. Eur.; analytical standard; JIS special grade; PESTANAL®, analytical standard; puriss. p.a.; purum; REAGENT
• Packaging: ampule of 1000 mg
• Suitability: passes test for suitability for Mg decision
• Ignition Residue: ≤0.05%; ≤0.05% (as SO4)
• Impurities: ≤0.05% insol. Alcohol; ≤0.05% insoluble in ethanol
• Antion Traces: chloride (Cl-): ≤10 mg/kg; chloride (Cl-): ≤20 mg/kg; sulfate (SO42-): ≤0.02%; sulfate (SO42-): ≤100 mg/kg
• Quality: for the detection and determination of Al, Mg and others
• Empirical Formula (Hill Notation): C9H7NO

DETAILS

MP Biomedicals - 05213232

MP Biomedicals Rare Chemical collection

MP Biomedicals - 02152569

ACS Reagent Grade

MP Biomedicals - 02151310

Free Base
Purity: 99+%
Light yellow crystals

Sigma Aldrich - H58307

Application
Chelating agent

Sigma Aldrich - 252565

Packaging
50, 250 g in glass bottle

Sigma Aldrich - 36524

Legal Information
PESTANAL is a registered trademark of Sigma-Aldrich Laborchemikalien GmbH

Sigma Aldrich - H6878

Application
Used as a lipophilic monoprotic bidentate chelating agent.
Biochem/physiol Actions
RNA 合成抑制剂，可作为杀灭须癣毛癣菌、疣孢漆斑菌和绿色木霉菌的杀真菌剂。抗真菌反应机理不明确，但与结构有关。
包装
25, 100, 500 g in glass bottle

Sigma Aldrich - 164984

Application
Metal-chelating agent
Packaging
100 g in glass bottle

REFERENCES

• Chelating ligand.