2-amino-3-hydroxypropanoic acid

• ChemBase ID: 69380
• Molecular Formular: C3H7NO3
• Molecular Mass: 105.09258
• Monoisotopic Mass: 105.04259309
• SMILES: C(=O)(C(N)CO)O
• Canonical SMILES: OCC(C(=O)O)N
• InChI: InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)
• InChIKey: MTCFGRXMJLQNBG-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: 2-amino-3-hydroxypropanoic acid
• IUPAC Traditional name: serin
• Synonyms: DL-2-Amino-3-hydroxypropionic acid; DL-Serine; (±)-2-Amino-3-hydroxypropionic acid; (+/-)-2-Amino-3-hydroxypropionic acid; H-DL-Ser-OH; (R)-2-Amino-3-hydroxypropanoic acid; 2-amino-3-hydroxypropanoic acid; DL-Serine; (±)-2-氨基-3-羟基丙酸; DL-丝氨酸

Database IDs

• CAS Number: 312-84-5; 302-84-1
• EC Number: 206-130-6
• MDL Number: MFCD00004269; MFCD00064223
• Beilstein Number: 1721402; 1721405
• Merck Index: 148460
• PubChem SID: 24899600; 24899650; 162035106
• PubChem CID: 617

CALCULATED PROPERTIES

• LogD (pH = 7.4): -3.8992038
• Log P: -3.8877351
• Molar Refractivity: 22.041 cm^3
• Polarizability: 9.0643015 Å^3
• Polar Surface Area: 83.55 Å^2
• Rotatable Bonds: 2
• Lipinski's Rule of Five: true
• Acid pKa: 2.03399
• H Acceptors: 4
• H Donor: 3
• LogD (pH = 5.5): -3.8875728

PROPERTIES

Physical Property

• Melting Point: 230-240 °C (dec.); 240 °C (dec.)(lit.); 246°C (dec.); ca 240°C dec.
• Density: 1.537 g/ml

Safety Information

• Storage Condition: Room Temperature (15-30°C)
• Storage Warning: IRRITANT
• German water hazard class: 1
• TSCA Listed: false; 是
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Product Information

• Purity: ≥98% (TLC); ≥99.0% (NT); 95+%; 98%; 99%
• Grade: puriss.
• Suitability: suitable for cell culture; suitable for insect cell culture
• Linear Formula: HOCH2CH(NH2)COOH

DETAILS

MP Biomedicals - 02102868

Crystalline

MP Biomedicals - 05218274

MP Biomedicals Rare Chemical collection

Sigma Aldrich - S5386

Application
For use in insect and mammalian cell culture applications where the pure L-form is not required.

Sigma Aldrich - S4375

Biochem/physiol Actions
NMDA agonist acting at the glycine site; precursor of glycine by serine hydroxymethyltransferase
包装
1 kg in poly bottle
100 g in poly bottle