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7487-88-9 molecular structure
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magnesium(2+) ion sulfate

ChemBase ID: 535
Molecular Formular: MgO4S
Molecular Mass: 120.3676
Monoisotopic Mass: 119.93677118
SMILES and InChIs

SMILES:
[Mg+2].[O-]S(=O)(=O)[O-]
Canonical SMILES:
[O-]S(=O)(=O)[O-].[Mg+2]
InChI:
InChI=1S/Mg.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2
InChIKey:
CSNNHWWHGAXBCP-UHFFFAOYSA-L

Cite this record

CBID:535 http://www.chembase.cn/molecule-535.html

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NAMES AND DATABASE IDS

NAMES AND DATABASE IDS

Names Database IDs
IUPAC name
magnesium(2+) ion sulfate
IUPAC Traditional name
magnesium(2+) sulfate
magnesium(2+) ion sulfate
Brand Name
Elliotts B Solution
Epsom salts
Hair salt
Kieserite [as monohydrate]
Sal amarum
Sal anglicum
Sal catharticum
Sal seidlitense
Salts of England
Sel d'angleterre
Synonyms
Bitter salt
Magnesium sulfate anhydrous
Magnesium sulfate dried
Magnesium sulfate heptahydrate
Magnesium sulphate
Magnesium Sulphate Hydrate
Magnesium Sulphate Heptahydrate
Magnesium Sulfate
Sulfuric Acid Magnesium Salt (1:1)
Epsom Salts
MAGNESIUM SULFATE ANHYDROUS
Magnesium sulfate, dried, contains ca 1-2 mol water of hydration
Magnesium sulfate, anhydrous
Magnesium sulfate solution
Magnesium sulfate
Epsom salt (heptahydrate)
Bitter salts
Magnesium sulfate concentrate
Magnesium sulfate hydrate
Magnesium sulfate solution
ISA (ionic strength adjustment solution: 1 M MgSO4)
Epsom salt
Magnesium sulfate heptahydrate
硫酸镁, 干的, 含有大概 1-2 个结晶水
无水硫酸镁
硫酸镁 溶液
硫酸镁
硫酸镁 水合物
硫酸镁 溶液
ISA(离子强度调节溶液:1M MgSO4)
七水硫酸镁
CAS Number
7487-88-9
22189-08-8
10034-99-8
EC Number
231-298-2
231-791-2
231-104-6
MDL Number
MFCD00011110
MFCD00149787
MFCD00149785
Merck Index
145691
PubChem SID
24882401
160963998
24882418
24852493
24860732
24896841
24852194
24897227
46508411
24896751
24882414
24848014
24863818
24897165
PubChem CID
24083
CHEBI ID
32599
ATC CODE
A06AD04
A12CC02
B05XA05
D11AX05
V04CC02
CHEMBL
1200456
Chemspider ID
22515
DrugBank ID
DB00653
Unique Ingredient Identifier
ML30MJ2U7I
Wikipedia Title
Magnesium_sulfate

CALCULATED PROPERTIES

CALCULATED PROPERTIES

JChem
Acid pKa -3.034349  H Acceptors
H Donor LogD (pH = 5.5) -5.569452 
LogD (pH = 7.4) -5.594027  Log P -0.841552 
Molar Refractivity 11.5274 cm3 Polarizability 6.037845 Å3
Polar Surface Area 80.26 Å2 Rotatable Bonds
Lipinski's Rule of Five true 

PROPERTIES

PROPERTIES

Physical Property Safety Information Product Information Bioassay(PubChem)
Solubility
anhydrous
26.9 g/100 mL (0 °C)
25.5 g/100 mL (20 °C)
heptahydrate
71 g/100 mL (20 °C) in water
expand Show data source
1.16 g/100 mL (18 °C, ether)
slightly soluble in alcohol, glycerol
insoluble in acetone
expand Show data source
710 mg/mL expand Show data source
H2O: soluble1 M at 20 °C, clear, colorless expand Show data source
Apperance
Powder expand Show data source
powder (very fine) expand Show data source
powder and chunks expand Show data source
slightly gray grit expand Show data source
white crystalline solid expand Show data source
Melting Point
1124 °C (anhydrous, decomp)
200 °C (monohydrate, decomp)
150 °C (heptahydrate, decomp)
2 °C (11-hydrate, decomp)
expand Show data source
1124°C dec. expand Show data source
ca. 150 - 200 °C with decomposition (hydrated salt MgSO4) expand Show data source
Density
1.07 g/mL at 20 °C expand Show data source
1.68 expand Show data source
2.66 expand Show data source
2.66 g/cm3 (anhydrous)
2.445 g/cm3 (monohydrate)
1.68 g/cm3 (heptahydrate)
1.512 g/cm3 (11-hydrate)
expand Show data source
ca. 1.68 g/cm3 (hydrated salt MgSO4) expand Show data source
Refractive Index
1.523 (monohydrate)
1.433 (heptahydrate)
expand Show data source
Vapor Pressure
<0.1 mmHg ( 20 °C) expand Show data source
Vapor Density
<0.01 (vs air) expand Show data source
Absorption Wavelength
λ: 260 nm Amax: 0.01 expand Show data source
λ: 260 nm Amax: 0.026 expand Show data source
λ: 280 nm Amax: 0.01 expand Show data source
λ: 280 nm Amax: 0.025 expand Show data source
Hydrophobicity(logP)
-0.91 expand Show data source
Odor
odorless expand Show data source
pH
5.0-7.0 (25 °C) expand Show data source
6.5-8.5 (25 °C, 1 M in H2O) expand Show data source
Storage Condition
Room Temperature (15-30°C), Desiccate expand Show data source
Storage Warning
Hygroscopic expand Show data source
RTECS
OM4500000 expand Show data source
OM4508000 expand Show data source
MSDS Link
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
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Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
German water hazard class
1 expand Show data source
nwg expand Show data source
TSCA Listed
expand Show data source
EU Index
Not listed expand Show data source
Personal Protective Equipment
Eyeshields, Gloves expand Show data source
Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) expand Show data source
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter expand Show data source
Purity
≥97% expand Show data source
≥97% (complexometric) expand Show data source
≥97% (KT) expand Show data source
≥98.0% expand Show data source
≥98.0% (KT) expand Show data source
≥99.0% expand Show data source
≥99.0% (calc. on dried material, KT) expand Show data source
≥99.5% expand Show data source
≥99.99% trace metals basis expand Show data source
99% expand Show data source
99.0-101.0% MgSO4 basis (in dried substance) expand Show data source
99.5% min expand Show data source
99+% expand Show data source
Concentration
~1 M in H2O expand Show data source
0.1 M MgSO4 expand Show data source
0.5 M expand Show data source
1.0 M MgSO4 expand Show data source
1.00 M±0.04 M expand Show data source
Grade
anhydrous expand Show data source
for molecular biology expand Show data source
puriss. expand Show data source
puriss. p.a. expand Show data source
purum expand Show data source
purum p.a. expand Show data source
reagent grade expand Show data source
ReagentPlus® expand Show data source
SAJ first grade expand Show data source
Certificate of Analysis
Download expand Show data source
Download expand Show data source
Packaging
pkg of 0.1 mol (24.648 g MgSO4 · 7H2O) expand Show data source
Suitability
complies for appearance of solution expand Show data source
plant cell culture tested expand Show data source
suitable for cell culture expand Show data source
suitable for insect cell culture expand Show data source
Impurities
≤0.0015% heavy metals (as Pb) expand Show data source
≤0.002% total nitrogen (N) expand Show data source
≤0.5% CaSO4 expand Show data source
≤0.8% K2SO4 expand Show data source
acidity or alkalinity, complies expand Show data source
DNases, none detected expand Show data source
insoluble matter, passes filter test expand Show data source
phosphatases, none detected expand Show data source
proteases, none detected expand Show data source
residual solvents, complies expand Show data source
RNases, none detected expand Show data source
Cation Traces
Al: ≤1 mg/kg expand Show data source
Al: ≤20 mg/kg expand Show data source
As: ≤0.1 mg/kg expand Show data source
As: ≤2 mg/kg expand Show data source
Ba: ≤1 mg/kg expand Show data source
Ba: ≤5 mg/kg expand Show data source
Bi: ≤1 mg/kg expand Show data source
Bi: ≤5 mg/kg expand Show data source
Ca: ≤200 mg/kg expand Show data source
Ca: ≤400 mg/kg expand Show data source
Ca: ≤5 mg/kg expand Show data source
Ca: ≤5000 mg/kg expand Show data source
Cd: ≤1 mg/kg expand Show data source
Cd: ≤5 mg/kg expand Show data source
Cd: ≤50 mg/kg expand Show data source
Co: ≤1 mg/kg expand Show data source
Co: ≤5 mg/kg expand Show data source
Co: ≤50 mg/kg expand Show data source
Cr: ≤1 mg/kg expand Show data source
Cr: ≤5 mg/kg expand Show data source
Cu: ≤1 mg/kg expand Show data source
Cu: ≤5 mg/kg expand Show data source
Cu: ≤50 mg/kg expand Show data source
Fe: ≤1 mg/kg expand Show data source
Fe: ≤10 mg/kg expand Show data source
Fe: ≤5 mg/kg expand Show data source
Fe: ≤50 mg/kg expand Show data source
heavy metals (as Pb): ≤5 ppm expand Show data source
K: ≤20 mg/kg expand Show data source
K: ≤200 mg/kg expand Show data source
K: ≤500 mg/kg expand Show data source
K: ≤8000 mg/kg expand Show data source
Li: ≤1 mg/kg expand Show data source
Li: ≤5 mg/kg expand Show data source
Mn: ≤1 mg/kg expand Show data source
Mn: ≤20 mg/kg expand Show data source
Mn: ≤5 mg/kg expand Show data source
Mo: ≤1 mg/kg expand Show data source
Mo: ≤5 mg/kg expand Show data source
Na: ≤100 mg/kg expand Show data source
Na: ≤20 mg/kg expand Show data source
NH4+: ≤20 mg/kg expand Show data source
Ni: ≤1 mg/kg expand Show data source
Ni: ≤5 mg/kg expand Show data source
Ni: ≤50 mg/kg expand Show data source
Pb: ≤1 mg/kg expand Show data source
Pb: ≤5 mg/kg expand Show data source
Pb: ≤50 mg/kg expand Show data source
Sr: ≤1 mg/kg expand Show data source
Sr: ≤5 mg/kg expand Show data source
Zn: ≤1 mg/kg expand Show data source
Zn: ≤5 mg/kg expand Show data source
Zn: ≤50 mg/kg expand Show data source
Antion Traces
chloride (Cl-): ≤100 mg/kg expand Show data source
chloride (Cl-): ≤400 mg/kg expand Show data source
chloride (Cl-): ≤5 mg/kg expand Show data source
chloride (Cl-): ≤50 mg/kg expand Show data source
nitrate (NO3-): ≤40 mg/kg expand Show data source
Foreign Activity
DNase, RNase, nickase and protease, none detected expand Show data source
Sterility
0.2 μm filtered expand Show data source
Shelf Life
(limited shelf life, expiry date on the label) expand Show data source
Loss on Drying
≤2% loss on ignition, 600 °C expand Show data source
≤26-36% loss on ignition, 500 °C expand Show data source
26-32% loss on drying, 400-500 °C expand Show data source
26-36% loss on ignition, 500°C expand Show data source
Quality
dried expand Show data source
meets analytical specification of DAC expand Show data source
volumetric expand Show data source
Factor
1.000 ±0.002 expand Show data source
λ
1 M in H2O expand Show data source
neat expand Show data source
Product Line
BioUltra expand Show data source
Linear Formula
MgSO4 · aq expand Show data source
Empirical Formula (Hill Notation)
MgSO4 expand Show data source

DETAILS

DETAILS

MP Biomedicals MP Biomedicals DrugBank DrugBank Wikipedia Wikipedia Sigma Aldrich Sigma Aldrich
MP Biomedicals - 02150136 external link
Anhydrous
Crystalline
MP Biomedicals - 02194699 external link
Cell Culture Reagent
Anhydrous
Crystalline
DrugBank - DB00653 external link
Item Information
Drug Groups approved
Description A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
Indication Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
Pharmacology Magnesium sulfate is a small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. Magnesium sulfate is gaining popularity as an initial treatment in the management of various dysrhythmias, particularly torsades de pointes, and dyrhythmias secondary to TCA overdose or digitalis toxicity.
Toxicity LD50 = 1200 mg/kg (rat, subcutaneous). May be harmful if swallowed. May act as an irritant. Adverse reactions include hypotension, ECG changes, diarrhea, urinary retention, CNS depression and respiratory depression.
Affected Organisms
Humans and other mammals
Biotransformation None
Half Life 43.2 hours (for newborns)
Protein Binding 25-30%
Elimination Magnesium is excreted solely by the kidney at a rate proportional to the serum concentration and glomerular filtration.
References
[Link]
Blitz M, Blitz S, Hughes R, Diner B, Beasley R, Knopp J, Rowe BH: Aerosolized magnesium sulfate for acute asthma: a systematic review. Chest. 2005 Jul;128(1):337-44. [Pubmed]
External Links
Wikipedia
RxList
Drugs.com
Sigma Aldrich - M3409 external link
Preparation Note
在 18 兆欧水中制备
Sigma Aldrich - 203726 external link
Packaging
25, 125 g in poly bottle
Sigma Aldrich - 63126 external link
General description
Visit our Titration Center to learn more.
Sigma Aldrich - 38146 external link
General description
Visit our Titration Center to learn more.
concentration after dilution to 1L: 0.1mol/L; amount of substance 0.1mol (24.648 g MgSO4 · 7H2O)
Sigma Aldrich - 63135 external link
Caution
may contain grey black particle
Sigma Aldrich - 58219 external link
General description
Visit our Sensor Applications portal to learn more.
Other Notes
Solution used to establish a constant ionic strength in a sample solution for determinations with ISE
Preparation Note
prepared with high purity salts
Sigma Aldrich - 34276 external link
General description
Visit our Titration Center to learn more.
Sigma Aldrich - 63137 external link
Other Notes
Procedure for chromosome and nuclei isolation for flow cytometric analysis1
Sigma Aldrich - M7506 external link
包装
1, 2 kg in poly bottle
12, 25 kg in poly drum
500 g in poly bottle
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC
Sigma Aldrich - 208094 external link
Packaging