4-hydroxybenzohydrazide

• ChemBase ID: 52453
• Molecular Formular: C7H8N2O2
• Molecular Mass: 152.15062
• Monoisotopic Mass: 152.05857751
• SMILES: C(=O)(c1ccc(cc1)O)NN
• Canonical SMILES: NNC(=O)c1ccc(cc1)O
• InChI: InChI=1S/C7H8N2O2/c8-9-7(11)5-1-3-6(10)4-2-5/h1-4,10H,8H2,(H,9,11)
• InChIKey: ZMZGIVVRBMFZSG-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: 4-hydroxybenzohydrazide
• IUPAC Traditional name: benzoylhydrazine, P-hydroxy; 4-hydroxybenzohydrazide
• Synonyms: 4-Hydroxybenzhydrazide; 4-Hydroxybenzoic Acid Hydrazide; 4-Hydroxybenzhydrazide; 4-Hydroxybenzoylhydrazine; p-HYDROXYBENZOIC ACID HYDRAZIDE; 4-HYDROXY BENZHYDRAZIDE; p-Hydroxybenzoic acid hydrazide; 4-Hydroxybenzhydrazide; 4-Hydroxybenzoic hydrazide; 4-Hydroxybenzohydrazide; 4-羟基苯甲酰肼

Database IDs

• CAS Number: 5351-23-5
• EC Number: 226-326-5
• MDL Number: MFCD00007605
• Beilstein Number: 473052
• PubChem SID: 162057216; 24278478
• PubChem CID: 1742

CALCULATED PROPERTIES

• Acid pKa: 8.40635
• H Acceptors: 3
• H Donor: 3
• LogD (pH = 5.5): 0.22235711
• LogD (pH = 7.4): 0.18329118
• Log P: 0.2238451
• Molar Refractivity: 41.6014 cm^3
• Polarizability: 15.213168 Å^3
• Polar Surface Area: 75.35 Å^2
• Rotatable Bonds: 1
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Melting Point: 260-264°C; 264-266 °C (dec.)(lit.); 264-266°C; 267°C (dec); ca 267°C dec.
• Fluorescence: λex 360 nm; λem 425 nm (after reaction with 5-hydroxymethyl-2-furaldehydezinc acetate); λex 360 nm; λem 425 nm (reacted with 5-hydroxymethyl-furaldehydezinc acetate)

Safety Information

• Storage Condition: Room Temperature (15-30°C)
• Storage Warning: IRRITANT
• European Hazard Symbols: Irritant (Xi)
• German water hazard class: 3
• Risk Statements: 36/37/38
• Safety Statements: 26-36; 26-37
• TSCA Listed: false; 否
• GHS Pictograms: GHS07
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• GHS Precautionary statements: P261-P305 + P351 + P338; P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves

Product Information

• Purity: ≥97%; ≥97.0% (T); 98%
• Suitability: suitable for fluorescence
• Linear Formula: HOC6H4CONHNH2

DETAILS

MP Biomedicals - 05224925

MP Biomedicals Rare Chemical collection

MP Biomedicals - 02104813

Crystalline

Sigma Aldrich - H9882

包装
25, 100 g in poly bottle

Sigma Aldrich - 54600

Other Notes
Reagent for the rapid automated determination of serum glucose1

REFERENCES

• Reagent for the determination of serum glucose.