NAMES AND DATABASE IDS
NAMES AND DATABASE IDS
Names Database IDs
IUPAC name
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1,8-dihydroxy-9,10-dihydroanthracene-9,10-dione
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IUPAC Traditional name
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altan
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danthron
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1,8-dihydroxy-9,10-dihydroanthracene-9,10-dione
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Brand Name
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Altan
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Antrapurol
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Bancon
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Chrysazin
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Chrysazine
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Criasazin
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Danivac
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Dantron
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Diaquone
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Dionone
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Dorbane
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Dorbanex
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Dorbantyl
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Duolax
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Istan
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Istin
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Istizin
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LTAN
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Laxanorm
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Laxanthreen
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Laxipur
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Laxipurin
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Modane
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Neokutin s
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Pastomin
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Prugol
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Regulin
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Roydan
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Scatron d
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Zwitsalax
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Synonyms
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Altan
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Antrapurol
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Chrysazin
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Danthrone
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Dantron
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Diaquone
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Dionone
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Dorbane
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Istin
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Istizin
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Laxanorm
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Laxanthreen
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Laxipur
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Laxipurin
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Modane
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NSC 38626
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NSC 646568
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NSC 7210
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Zwitsalax
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1,8-dihydroxyanthracene-9,10-dione
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Dantron
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1,8-Dihydroxyanthra-9,10-quinone
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Chrysazine
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1,8-Dihydroxyanthraquinone
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Danthron
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1,8-DIHYDROXYANTHRAQUINONE
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CHRYSAZIN PRACTICAL GRADE
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1,4,5,8-Tetroxyantraquinone
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1,8-Dihydroanthraquinone
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1,8-Dihydroxy-9,10-anthracenedione
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1,8-Dihydroxy-9,10-anthraquinone
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1,8-Dihydroxyanthra-9,10-quinone
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1,8-dihydroxyanthracene-9,10-dione
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1,8-Dihydroxyanthrachinon
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1,8-Dihydroxyanthrachinon [Czech]
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1,8-Dihydroxyanthraquinone
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Dantrona [inn-spanish]
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Dantrone [inn-french]
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Dantronum [inn-latin]
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DHAQ
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Dihydroxyanthraquinone
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Dioxyanthrachinonum
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Usaf nd-59
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Danthron
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Danivac
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Dantron
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丹蒽醌
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二羟蒽醌
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1,8-二羟基蒽醌
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CAS Number
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EC Number
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MDL Number
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Beilstein Number
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Merck Index
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PubChem SID
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PubChem CID
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CHEBI ID
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ATC CODE
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CHEMBL
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Chemspider ID
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DrugBank ID
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KEGG ID
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Unique Ingredient Identifier
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Wikipedia Title
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DATA SOURCES
DATA SOURCES
All Sources Commercial Sources Non-commercial Sources
CALCULATED PROPERTIES
CALCULATED PROPERTIES
JChem
ALOGPS 2.1
Acid pKa
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7.890132
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H Acceptors
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4
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H Donor
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2
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LogD (pH = 5.5)
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3.6098228
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LogD (pH = 7.4)
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3.483305
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Log P
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3.6115754
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Molar Refractivity
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65.1128 cm3
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Polarizability
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24.523813 Å3
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Polar Surface Area
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74.6 Å2
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Rotatable Bonds
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0
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Lipinski's Rule of Five
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true
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Log P
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2.98
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LOG S
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-2.9
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Solubility (Water)
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3.05e-01 g/l
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DETAILS
DETAILS
MP Biomedicals
DrugBank
Wikipedia
Sigma Aldrich
TRC
DrugBank -
DB04816
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Item |
Information |
Drug Groups
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withdrawn |
Description
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Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity. |
External Links |
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Sigma Aldrich -
D108103
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Packaging 100, 500 g in glass bottle Other Notes Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D108103.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin. |
REFERENCES
REFERENCES
From Suppliers
Google Scholar
PubMed
Google Books
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- • Grocholski, T., et al.: Biochem., 49, 934 (2009)
- • Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2009)
- • Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 87D, (ir)
- • Aldrich Library of NMR Spectra, 2nd edn., 1983, 2, 91B, (nmr)
- • Naylor, C.A. et al., J.A.C.S., 1931, 53, 4112
- • Aoyama, S. et al., Yakugaku Zasshi, 1932, 52, 17
- • Lish, P.M. et al., J. Am. Pharm. Assoc., 1958, 47, 371, (pharmacol)
- • Kido, H. et al., Anal. Chim. Acta, 1960, 23, 116, (ir)
- • Beynon, J.H. et al., Appl. Spectrosc., 1960, 14, 156, (ms)
- • Ruggieri, R., Anal. Chim. Acta, 1961, 25, 145, (use)
- • Prakesh, A., Z. Kristallogr., Kristallgeom., Kristallphys., Kristallchem., 1965, 122, 272, (cryst struct)
- • Fairbairn, J.W. et al., J. Pharm. Pharmacol., 1970, 22, 584, (pharmacol)
- • Idris, K.A. et al., Egypt. J. Chem., 1973, 67, (uv)
- • Morley, J.O. et al., J.C.S. Perkin 2, 1973, 1626, (pmr)
- • Fournier, G. et al., Phytochemistry, 1975, 14, 2099, (isol)
- • Breimer, D.D. et al., Pharmacology, 1976, 14, 30, (metab)
- • Case, M.T. et al., Drug Chem. Toxicol., 1978, 1, 89, (tox)
- • Berger, Y. et al., Org. Magn. Reson., 1978, 11, 375, (cmr)
- • Cameron, A.W. et al., Aust. J. Chem., 1982, 35, 2095, (synth)
- • Howard, D.F. et al., Naturwissenschaften, 1982, 69, 91, (isol)
- • Roman Ceba, M. et al., Mikrochim. Acta, 1983, 2, 85, (detn, Mg)
- • Mueller, K. et al., Arch. Pharm. (Weinheim, Ger.), 1984, 317, 120, (synth)
- • Gattuso, J.M. et al., Drug Saf., 1984, 10, 47, (rev)
- • Khanapure, S.P. et al., J.O.C., 1987, 52, 5685, (deriv, synth, pmr, ir)
- • Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 2970, (synonyms)
- • IARC Monog., 1990, 50, 265, (rev, tox)
- • Grunwell, J.R. et al., J.O.C., 1991, 56, 91, (synth, pmr)
- • Kahr, B. et al., Angew. Chem., Int. Ed., 1992, 31, 1, (tautom)
- • Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 1215
- • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DMH400
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PATENTS
PATENTS
PubChem Patent
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